The purpose of this study was to examine the rates of medication adherence among HIV-infected adolescents/young adults and to explore the relationship between negative affect, cognitive ability/ formal reasoning, and substance use on the medication adherence of these youth. Forty-two HIV-positive youth (25 males, 17 females; age range 16 - 24) currently taking antiretroviral medications were recruited to participate in a one-hour interview. Using the time-line follow-back calendar method, 66% of participants had missed a dose of medicine in the past week while 42% missed a dose 'yesterday'. Multiple regression analyses demonstrated that both depression and age of first marijuana use were statistically significant predictors of non-adherence ( < .01, = .326). Specifically, higher rates of depressive symptoms and younger age of first marijuana use predicted higher rates of non-adherence. Developmentally, 69% of the sample had yet to begin the transition from concrete thinking to formal or abstract reasoning. The results from this project demonstrate that adherence to antiretroviral medications continues to be a problem with HIV-infected youth. These results are an important first step toward the development of interventions aimed at increasing medication adherence among adolescents and young adults living with HIV.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334460 | PMC |
| http://dx.doi.org/10.1080/1354350042000326584 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Gender inequalities in prescribing and initiation patterns of guideline-recommended drugs after acute myocardial infarction.
BMC Public Health
January 2025
Grupo de Investigación en Servicios Sanitarios de Aragón (GRISSA), Fundación Instituto de Investigación Sanitaria de Aragón (IIS Aragón), Zaragoza, Spain.
Background: European guidelines recommend the prescription of certain drugs after acute myocardial infarction (AMI). The existence of gender differences in pharmacological treatment after an AMI has been described. This study aims to describe and analyse, using real-world data (RWD), whether there are gender differences in the prescribing patterns and initiation of treatment in secondary prevention after a first AMI, and which are the factors that explain these differences.
View Article and Find Full Text PDFThe factors influencing self-management in patients with depression: a qualitative research from China.
BMC Psychiatry
January 2025
School of Nursing, Jining Medical University, Jining, Shandong Province, China.
Background: As depressed patients often fail to seek help and obtain treatment on time for reasons such as stigma and lack of treatment resources, research on self-management for depressed patients is crucial. This study aimed to explore the factors influencing self-management in depression patients from the perspectives of both patients and psychiatric nurses.
Methods: Six depression patients and twelve psychiatric nurses were chosen for semi-structured interviews through a purposive sampling method from a tertiary Grade A psychiatric hospital in Shandong Province, China.
Digital Health for Asthma Management: Electronic Medication Monitoring for Adherence as a Case Example.
J Allergy Clin Immunol Pract
January 2025
Breathing Institute, Children's Hospital Colorado, Department of Pediatrics, Pediatric Pulmonary and Sleep Medicine Section, University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, CO. Electronic address:
Digital health is an umbrella term for components of healthcare utilizing computer platforms, software, connectivity and sensors to augment the recording, documentation and communication of clinical information. The functions of digital health may be viewed in three domains: 1) the repository for patient information, 2) monitoring devices and 3) communication tools. Monitoring devices have provided robust information as diagnostic and prognostic tools in office and hospital settings.
View Article and Find Full Text PDFThumb-sized 3D-Printed cymbal microneedle array (CyMA) for enhanced transdermal drug delivery.
Eur J Pharm Biopharm
January 2025
School of Mechanical and Electrical Engineering, Central South University, Changsha 410083, China; Department of Dermatology, Xiangya Hospital, Central South University, Changsha 410008, China; Hunan Engineering Research Center of Skin Health and Disease, Xiangya Hospital, Central South University, Changsha 410008, China. Electronic address:
Transdermal drug delivery presents a compelling alternative to both needle injection and oral ingestion of medication, as it enhances patient adherence and convenience through its non-invasive and painless administration method. The use of microneedles penetrates the barrier of the stratum corneum, facilitating the sustained delivery of drugs across the skin. However, their efficacy has been limited by the slow diffusion of molecules and often requires external triggers.
View Article and Find Full Text PDFPsychopathology trajectories and relapse in first episode schizophrenia with assured long-acting injectable adherence over 24 months.
Schizophr Res
January 2025
Faculty of Medicine and Health Sciences, Department of Psychiatry, Stellenbosch University, Tygerberg, 7500 Cape Town, South Africa.
Background: Relapse following a first episode of schizophrenia (FES) is common and often results in serious adverse psychosocial consequences. Treatment non-adherence is a key risk factor for relapse, but why relapse occurs despite antipsychotic treatment adherence remains unclear. This study examined the differences in FES psychopathology trajectories over 24-months with assured long-acting injectable antipsychotic (LAIA) treatment, to control for treatment adherence between those who relapsed and those who did not and what moderates these group differences.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!