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Should we be more aggressive in the therapy against cardiovascular risk factors? Should we prescribe statin and aspirin for every diabetic patient, or is it time for a polypill?
Diabetes Care
February 2008
Heart and Diabetes Center NRW, Ruhr University Bochum, Bad Oeynhausen, Germany.
The reality of primary and secondary prevention of cardiovascular complications in people with diabetes is alarming, even in developed countries with a well-structured medical system. Even though therapeutic targets have been more clearly defined during the last decades, their implementation is still suboptimal. Financial and structural reasons, insufficient information of physicians and patients, along with a low compliance of the latter are only a few reasons that have been incriminated.
View Article and Find Full Text PDFThe future of metabolic syndrome and cardiovascular disease prevention: polyhype or polyhope? Tales from the polyera.
Horm Metab Res
September 2007
Unilever Corporate Research, Colworth Park, Sharnbrook, Bedfordshire, MK441LQ, UK.
Recently society has been witnessing the rise of a new era in the prevention and treatment of the metabolic syndrome and cardiovascular disease: the Polyera. This new era started when a promising concept - the Polypill - was introduced by Wald et al. in 2003.
View Article and Find Full Text PDFThe Polymeal: a more natural, safer, and probably tastier (than the Polypill) strategy to reduce cardiovascular disease by more than 75%.
BMJ
December 2004
Department of Public Health, Erasmus MC University Medical Centre Rotterdam, PO Box 1738, 3000 DR Rotterdam, Netherlands.
Objective: Although the Polypill concept (proposed in 2003) is promising in terms of benefits for cardiovascular risk management, the potential costs and adverse effects are its main pitfalls. The objective of this study was to identify a tastier and safer alternative to the Polypill: the Polymeal.
Methods: Data on the ingredients of the Polymeal were taken from the literature.
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