Traditional testing methods have limited epidemiologic studies of tuberculosis among free-living primates. PCR amplification of insertion element IS6110 of Mycobacterium tuberculosis from fecal samples was evaluated as a noninvasive screening test for tuberculosis in primates. Active tuberculosis was detected among inoculated macaques and naturally exposed chimpanzees, demonstrating the utility of this test.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344255 | PMC |
| http://dx.doi.org/10.3201/eid2103.140052 | DOI Listing |
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