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In January, 2014, increased mortality was reported in piglets with acute diarrhea on an Ontario farm. Villus atrophy in affected piglets was confined to the small intestine. Samples of colon content were PCR-positive for porcine epidemic diarrhea virus (PEDV). Other laboratory tests did not detect significant pathogens, confirming this was the first case of PED in Canada.
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AMB Express
March 2025
National Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, 430070, Hubei, China.
African swine fever (ASF) is a contagious viral disease in pigs, caused by the African swine fever virus (ASFV). Currently, there are no effective vaccines and drugs for ASFV, making diagnostic methods crucial for the prevention and control of ASF. In this study, the ASFV p30 protein was successfully expressed using a prokaryotic expression system and used as an immunogen to prepare monoclonal antibody (mAb) 2A5.
View Article and Find Full Text PDFVet Microbiol
March 2025
Key Laboratory of Animal Diseases Diagnostic and Immunology, Ministry of Agriculture, MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China; Jiangsu Co‑Innovation Center for the Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, Yangzhou 225009, China. Electronic address:
Porcine epidemic diarrhea virus (PEDV) is a porcine enteropathogenic coronavirus that causes significant economic losses in many Asian and European countries. It is characterized by lethal watery diarrhea and high mortality rate in piglets. Serum amyloid P component (SAP), a member of acute response phase protein (APP) family, has been reported to play a crucial role in innate immune response against various microbial pathogens.
View Article and Find Full Text PDFVet Q
December 2025
Facultad de Ciencias de la Naturaleza, Universidad San Sebastián, Concepción, Chile.
Trichinellosis is a significant zoonotic disease worldwide, with pigs as a primary reservoir host of human infection. Backyard pigs are particularly at risk due to their exposure to muscle tissue containing larvae from synanthropic micromammals or home slaughter waste. In Chile, veterinary inspections of domestically slaughtered pigs are mainly conducted in veterinary clinics using muscle samples provided by farmers or consumers.
View Article and Find Full Text PDFPorcine Health Manag
March 2025
Field Station for Epidemiology, University of Veterinary Medicine, Foundation, Büscheler Str. 9, 49456, Hannover, Bakum, Germany.
Background: Pain in pigs needs to be managed and treated to the benefit of individual pigs. It is imperative for veterinarians and farmers to assure that pigs do not suffer from unnecessary pain that can be relieved. This review focusses on pain related to spontaneously occurring diseases and injuries since this topic is often neglected.
View Article and Find Full Text PDFJ Virol
March 2025
College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Porcine epidemic diarrhea virus (PEDV) is a primary cause of viral diarrhea in neonatal piglets, leading to substantial economic losses in the swine industry globally. It primarily targets epithelial cells of the small intestine, compromising intestinal function and resulting in the death of affected animals. As mitochondria are essential for maintaining gut health, this study investigates the effects of PEDV infection on mitochondrial function in small intestinal epithelial cells and its subsequent impacts.
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