Hepatitis C virus contains a second open reading frame within the core gene, designated core+1/ARF. Here we demonstrate for the first time expression of core+1/ARF protein in the context of a bicistronic JFH1-based replicon and report the production of two isoforms, core+1/L (long) and core+1/S (short), with different kinetics.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403472 | PMC |
| http://dx.doi.org/10.1128/JVI.02351-14 | DOI Listing |
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