Halicephalobus gingivalis (previously Micronema deletrix) is a free-living nematode known to cause opportunistic infections, mainly in horses. Human infections are very rare, but all cases described to date involved fatal meningoencephalitis. Here we report the first case of H. gingivalis infection in an Australian human patient, confirmed by nematode morphology and sequencing of ribosomal DNA. The implications of this case are discussed, particularly, the need to evaluate real-time PCR as a diagnostic tool.
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http://dx.doi.org/10.1128/JCM.00032-15 | DOI Listing |
Vet Res Commun
October 2024
Microbiology and Infectious Diseases Laboratory (MIDlab), ICBAS - School of Medicine and Biomedical Sciences, Porto University, Porto, Portugal.
The life-cycle of the parasitic forms of Halicephalobus gingivalis is yet to be fully understood. In cases where there is evidence to support the presence of eggs from this parasite or its DNA in the faeces of equines, a thorough investigation of the clinical status and gastro-intestinal tract of the affected animals is warranted, as well as detailed descriptions of the employed coprological technique. Since reports of the identification of H.
View Article and Find Full Text PDFParasites Hosts Dis
February 2024
Department of Veterinary Medicine, Federal University of Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul State 79070-900, Brazil.
Halicephalobus gingivalis is a free-living nematode that occasionally causes infections in horses. We report a rare case of limb fracture of horse caused by infection with H. gingivalis.
View Article and Find Full Text PDFActa Vet Scand
December 2023
Department of Microbiology, National Veterinary Institute (SVA), Uppsala, Sweden.
Background: Halicephalobus gingivalis is a nematode with zoonotic potential which can cause fatal opportunistic infections in various mammals. The parasite has never been diagnosed in Sweden, in any species, prior to the presented case.
Case Presentation: An imported 21-year-old Icelandic mare developed severe neurological signs.
Vet Res Commun
February 2024
Department of Pathobiology, Faculty of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, Iran.
Background: Parasitic infections pose significant threats to humans' and animals' well-being worldwide. Among these parasites, Halicephalobus spp., a genus of nematodes, has gained attention due to its ability to cause severe infections in various animal species, including horses.
View Article and Find Full Text PDFVet Parasitol Reg Stud Reports
April 2023
Biomedical and Diagnostic Sciences, University of Tennessee, 2407 River Drive, Room A233, Knoxville, TN 37996, USA.
A 17-year-old female grade pony presented to University of Tennessee Veterinary Medical Center in May of 2021 for evaluation of multifocal, firm, sessile, circular lesions of various diameters on the ventrum and flank. The lesions had been present for two weeks at presentation. An excisional biopsy found numerous adult and larval rhabditid nematodes most consistent with Halicephalobus gingivalis.
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