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Amitriptyline for the treatment of vulvodynia in patients with vulvar lichen sclerosus: a case series of 20 patients.
Int J Dermatol
January 2025
Dermatology Unit, Department of Mental and Physical Health and Preventive Medicine, University of Campania Luigi Vanvitelli, Naples, Italy.
Vulvar Lichen Sclerosus (VLS) is a chronic autoimmune disease that often leads to vulvodynia, a debilitating chronic pain condition in the vulvar region. Treating vulvodynia in the context of VLS presents a significant therapeutic challenge due to the lack of standardized protocols. This article presents a case series of 20 women treated with amitriptyline for vulvodynia secondary to VLS, accompanied by an extended review of the literature.
View Article and Find Full Text PDFGynaecologic oncology referrals to specialist palliative care in a tertiary referral centre: population, characteristics and outcomes.
BMJ Support Palliat Care
November 2024
Palliative Medicine, Cork University Hospital, Cork, Ireland.
Background: The early integration of a specialist palliative care team is demonstrated to have numerous benefits for patients. These extend beyond end-of-life care to include reducing depressive symptoms, improving quality of life and reducing unnecessary interventions.
Aims: This study aims to characterise the patient population referred to the specialist palliative care service with a diagnosis of gynaecological cancer.
Recurrent Allergic Contact Dermatitis to Bacitracin Used in Pocket Irrigation During Breast Reconstruction Surgery.
Plast Surg (Oakv)
November 2024
Department of Dermatology and Skin Science, University of British Columbia, Vancouver, BC, Canada.
Allergic contact dermatitis (ACD) is a delayed-type hypersensitivity reaction that presents as a pruritic eczematous rash occurring 24 to 48 h after allergen exposure. It is a surgical complication that can impact people's quality of life after plastic surgeries. A 44-year-old female with right breast cancer presented with three recurrent episodes of severe pruritic cutaneous eczematous eruption over her right breast extending down to her trunk and vulva each time soon after her multiple breast surgeries.
View Article and Find Full Text PDFL1CAMs are immunoglobulin superfamily cell adhesion molecules that ensure proper nervous system development and function. In addition to being associated with the autism and schizophrenia spectrum disorders, mutations in the L1CAM family of genes also underlie distinct developmental syndromes with neurological conditions, such as intellectual disability, spastic paraplegia, hypotonia and congenital hydrocephalus. Studies in both vertebrate and invertebrate model organisms have established conserved neurodevelopmental roles for L1CAMs; these include axon guidance, dendrite morphogenesis, synaptogenesis, and maintenance of neural architecture, among others.
View Article and Find Full Text PDFn. sp. (Strongylida: Molineidae) in the bat (Leach; Chiroptera: Vespertilionidae) from China.
Front Vet Sci
September 2024
Hebei Key Laboratory of Intractable Pathogens, Shijiazhuang, China.
A new species of nematode, n.sp., parasite of the genus , is described based on specimens recovered from the small intestine of Leach, 1822 (Chiroptera: Vespertilionidae) in Longmen County, Guangdong Province, China.
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