Two new chalcones from Shuteria sinensis.

Nat Prod Res

a School of Traditional Chinese Medicine, Yunnan University of Traditional Chinese Medicine, Kunming 650500 , Yunnan , P.R. China.

Published: December 2015

Two new chalcones, 2',3,4,4'-tetrahydroxy-2-prenylchalcone (1) and 3-methoxy-2',4,4'-trihydroxy-2-prenylchalcone (2), together with two known compounds, munsericin (3) and 3,4-dihydroxylonchocarpin (4), were isolated from the ethanol extract of the whole plant of Shuteria sinensis. Their structures were identified by spectroscopic analysis methods, such as 1D and 2D NMR, along with HR-MS data. Glucose metabolism activity of four compounds was tested, compounds 3 and 4 showed effect on the glucose consumption of insulin-resistant HepG2 cells.

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Source
http://dx.doi.org/10.1080/14786419.2015.1012718DOI Listing

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