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Surgical treatment of Gorham-Stout disease combined with scoliosis: a case report and literature review.
BMC Musculoskelet Disord
December 2024
Department of Orthopaedic Surgery, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Science, Beijing, People's Republic of China.
Background: Gorham-Stout disease (GSD) is a rare disease characterized by osteolysis and lymphatic malformations. GSD involving the spine is exceptionally rare and lacks a standard cure. The aim of this article was to report a case of GSD with scoliosis treated via corrective surgery and medication.
View Article and Find Full Text PDFEffectiveness of Intradiscal Regenerative Medicine Therapies for Long-Term Relief of Chronic Low Back Pain: A Systematic Review and Meta-Analysis.
Pain Physician
December 2024
Massachusetts General Hospital, Harvard Medical School, Boston, MA.
Article Synopsis
- Recent research highlights the potential of biologic treatments like mesenchymal stem cells (MSCs) and platelet-rich plasma (PRP) for relieving low back pain by promoting healing in intervertebral discs.
- A systematic review and meta-analysis evaluated the effectiveness of MSC and PRP injections for chronic low back and leg pain, analyzing data from various credible sources.
- The findings included 8 randomized controlled trials and 8 observational studies, revealing fair evidence quality but noting a lack of high-quality studies, suggesting a moderate recommendation for these treatments.
Analysis of Risk Factors Causing Adjacent Disc Degeneration After Percutaneous Kyphoplasty for Osteoporotic Vertebral Compression Fractures.
J Pain Res
November 2024
Department of Orthopedics, Beijing Chaoyang Hospital, Capital Medical University, Beijing, People's Republic of China.
Purpose: Adjacent disc degeneration (ADD) is a common postoperative complication after percutaneous kyphoplasty (PKP). However, risk factors for ADD after PKP have not been reported. This study aimed to determine whether osteoporotic vertebral compression fracture (OVCF) following PKP is associated with a high risk for ADD and to identify the risk factors for ADD.
View Article and Find Full Text PDFArticle Synopsis
- The study examines the connection between forearm bone mineral density (BMD) and the risk of adjacent vertebral re-fracture after percutaneous kyphoplasty (PKP) in patients with osteoporotic vertebral compression fractures (OVCF).
- It involved a retrospective analysis of 198 OVCF patients, categorizing them into re-fracture and no-fracture groups while assessing various health and surgical factors.
- Findings indicated a 17.2% re-fracture rate following PKP, with notable differences in health conditions and bone density measurements between the two groups, highlighting the importance of forearm BMD as a potential predictor for re-fractures.
A porohyperelastic scheme targeted at High-Performance Computing frameworks for the simulation of the intervertebral disc.
Comput Methods Programs Biomed
February 2025
Department of Computer Applications in Science and Engineering (CASE), Barcelona Supercomputing Center, Plaça d'Eusebi Güell, 1-3, Barcelona, 08034, Spain; ELEM Biotech SL, Pier01 - Palau de Mar - Plaça Pau Vila, 1, Barcelona, 08003, Spain.
Background And Objective: The finite element method is widely used for studying the intervertebral disc at the organ level due to its ability to model complex geometries. An indispensable requirement for proper modelling of the intervertebral disc is a reliable porohyperelastic framework that captures the elaborate underlying mechanics. The increased complexity of such models requires significant computational power that is available within high-performance computing systems.
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