AI Article Synopsis
- The study aimed to find out if prostatic carcinoma (PCa) can be detected using routine contrast-enhanced CT (CECT) scans.
- A total of 63 patients with PCa were assessed by two blinded radiologists, focusing on the detection of specific nodules in the prostate.
- The results showed that CECT had good sensitivity for detecting higher-grade PCa (Gleason Score ≥7), with a moderate level of agreement between radiologists and a low rate of false positives.
Article Abstract
Objectives: To determine if prostatic carcinoma (PCa) is detectable at routine contrast-enhanced CT (CECT).
Materials And Methods: With institutional review board approval, 63 consecutive PCa patients underwent CECT before therapy. Two blinded radiologists assessed for rounded focal enhancing peripheral zone nodules. Diagnostic accuracy and inter-observer agreement were compared by Gleason Score (GS).
Results: Overall sensitivity was 63-76% with moderate agreement, K=0.42. The false-positive rate was 15%. Sensitivities and agreement for GS 9-10, 7-8 and 6 PCa were 84-91%, 73-84%, 41-71%, (P=.023 and .001) and K=(0.72, 0.69, 0.23).
Conclusions: CECT has good sensitivity for detecting GS ≥7 PCa with substantial agreement and a low false-positive rate.
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| http://dx.doi.org/10.1016/j.clinimag.2015.01.008 | DOI Listing |
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