Transfusion-Related Acute Lung Injury After IVIG for Myasthenic Crisis.

Neurocrit Care

Division of Pulmonary and Critical Care Medicine, Mayo Clinic, 200 First Street SW RO_OL_2_115CCS, Rochester, MN, 55905, USA,

Published: October 2015

Background: A 26-year-old female with myasthenic crisis developed transfusion-related acute lung injury (TRALI) after she was treated with intravenous immunoglobulin.

Methods: Case report.

Results: Respiratory status markedly worsened with each intravenous immunoglobulin (IVIG) administration and progressing from a need to use bilevel positive airway pressure (BiPAP) to intubation. Pulmonary function tests improved during this episode.

Conclusions: IVIG may cause TRALI and due to subtle clinical findings can be mistaken for neuromuscular respiratory failure.

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Source
http://dx.doi.org/10.1007/s12028-015-0115-zDOI Listing

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