Sentinel lymph node biopsy for head and neck Merkel cell carcinoma: a preliminary study.

Eur Ann Otorhinolaryngol Head Neck Dis

Service de Chirurgie Maxillo-Faciale, Centre François-Xavier-Michelet, Hôpital Pellegrin, place Amélie-Raba-Léon, 33076 Bordeaux cedex, France.

Published: April 2015

Introduction: A retrospective preliminary study assessed the feasibility of sentinel lymph node biopsy (SLNB) in the management of Merkel cell carcinoma (MCC) of the head and neck.

Patients And Methods: Twelve patients with stage I or II head and neck MCC underwent SLNB over a 4-year period.

Results: Only 1 of the 12 patients had a positive SLNB. The sentinel node was not identified in 3 patients. Two of the 8 patients with negative SLNB showed regional lymph node recurrence within 2years. One patient died during follow-up.

Conclusion: Merkel cell carcinoma is an uncommon but highly aggressive pathology; management protocols have been based on small series. The role of SLNB in the management of MCC remains to be defined.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.anorl.2015.01.005DOI Listing

Publication Analysis

Top Keywords

lymph node
12
merkel cell
12
cell carcinoma
12
sentinel lymph
8
node biopsy
8
head neck
8
preliminary study
8
slnb management
8
slnb
5
node
4

Similar Publications

Bovine tuberculosis is mainly caused by Mycobacterium bovis. Bacillus Calmette-Guérin (BCG) is an attenuated strain of M. bovis which provides variable disease protection.

View Article and Find Full Text PDF

Objective: To evaluate the feasibility and tolerance of ultra-hypofractionated SABR (stereotactic ablative radiation therapy) protocol following radical prostatectomy.

Patients And Methods: We included patients undergoing adjuvant or salvage SABR between April 2019 and April 2023 targeting the surgical bed and pelvic lymph nodes up to a total dose of 36.25 Gy (7.

View Article and Find Full Text PDF

Computed tomography-based nomogram for estimating progression-free survival probability in bladder cancer patients undergoing partial cystectomy.

Abdom Radiol (NY)

January 2025

Department of Radiology, Tianjin First Central Hospital, Tianjin Institute of Imaging Medicine, School of Medicine, Nankai University, Tianjin, China.

Purpose: To establish a prognostic model to estimate progression-free survival (PFS) probability in bladder cancer (BCa) patients undergoing partial cystectomy.

Material And Methods: Consecutive patients who underwent partial cystectomy between August 2012 and April 2021 were enrolled. The primary endpoint was PFS during the follow-up.

View Article and Find Full Text PDF

Objectives: To develop a nomogram based on the radiomics features of tumour and perigastric adipose tissue adjacent to the tumor in dual-layer spectral detector computed tomography (DLCT) for lymph node metastasis (LNM) prediction in gastric cancer (GC).

Methods: A retrospective analysis was conducted on 175 patients with gastric adenocarcinoma. They were divided into training cohort (n = 125) and validation cohort (n = 50).

View Article and Find Full Text PDF

Objectives: The Scrotal and Penile Imaging Working Group (SPIWG) of the European Society of Urogenital Radiology (ESUR) aimed to formulate recommendations on the imaging modalities and minimal technical requirements for abdominopelvic imaging in the follow-up of adult patients treated for testicular germ-cell tumors (TGCT).

Methods: The SPIWG members performed an extensive literature search, reviewed the current clinical practice, and reached a consensus based on the opinions of experts in the field.

Results: Recurrence in patients treated for TGCT mainly occurs in retroperitoneal lymph nodes (LNs).

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!