Streptococcus pneumoniae is a rare cause of appendicitis.We report apneumococcal appendicitis with secondary peritonitis in a human immunodeficiency virus–positive adult, with favorable outcome after surgery and antibiotic therapy. Secondary peritonitis is frequently complication of S pneumoniae appendicitis in the few reported cases,and no specific risk factor has been identified so far.
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SPD_0410 negatively regulates capsule polysaccharide synthesis and virulence in D39.
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