One new flavonoid, 5,6,7-trimethoxyflavone-8-O-β-D-glucopyranoside (1), along with six known compounds 2-7, was isolated from Oroxylum indicum. Their structures were determined on the basis of spectral data. The antibacterial activities of compounds 1-4 were studied. Compounds 1 and 3 showed medium antibacterial activity against Staphylococcus aureus with MIC/MBC at 32-128 μg/ml.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1080/14786419.2015.1007976 | DOI Listing |
Anticancer Agents Med Chem
December 2024
Department of Biotechnology, Manipur University, Canchipur, Manipur, 795003, India.
Background: As the number of new cancer cases increases every year, there is a necessity to develop new drugs for the treatment of different types of cancers. Plants' resources are considered to be huge reservoirs for therapeutic agents in nature. Among all the medicinal plants, Oroxylum indicum is one of the most widely used medicinal plants in India, China, and Southeast Asian countries.
View Article and Find Full Text PDFFront Pharmacol
October 2024
Jiangsu Provincial Key Laboratory for TCM Evaluation and Translational Research, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, Jiangsu, China.
Introduction: Scutellarein (Scu) is a natural occurring flavonoid found in multiple traditional Chinese medicines such as indicum (L.) Kurz and , with various pharmacological activities including anti-inflammation, anti-oxidation and myocardial protection. Here, we investigated the therapeutic efficacy of Scu on ulcerative colitis (UC) and the underlying mechanism.
View Article and Find Full Text PDFIndian J Clin Biochem
October 2024
Department of Pharmaceutical Sciences, Dibrugarh University, Dibrugarh, Assam 786004 India.
a well-known traditional medicinal plant which is used to alleviate various kinds of diseases in Asia. The study aimed to identify bioactive compounds present in stem bark using HPTLC technique. Further, the cytotoxic effects of the plant extracts were determined against HeLa (human cervical carcinoma) cell lines.
View Article and Find Full Text PDFJ Adv Pharm Technol Res
July 2024
Department of Pharmacognosy, Faculty of Pharmacy, Mahidol University, Bangkok, Thailand.
A topical antimicrobial ointment was developed from the fruit extract of and was evaluated for its antibacterial and wound-healing effects and acute toxicity in animal models. fruit and seed extracts exhibited antibacterial activities against clinically isolated bacteria and showed antioxidant activities. To develop a topical antimicrobial ointment from the fruit extract of and evaluate for its antibacterial and wound-healing effects.
View Article and Find Full Text PDFNat Prod Res
August 2024
Phytochemistry Division, CSIR-Central Institute of Medicinal and Aromatic Plants, Lucknow, India.
The opioid receptors play a pivotal role in the treatment of several neuropsychiatric and neurological disorders. (L.) Kurtz is a very important medicinal plant with several therapeutic applications.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!