The samples collected from cats showing clinical signs suspected for feline panleukopenia infection were confirmed using various molecular techniques and virus isolation. The suspected samples were confirmed using feline parvovirus specific primers. The partial VP2 gene was submitted to GenBank for the first time in India (Accession number JQ684660.1). The PCR positive samples were further amplified using full length FPV VP2 gene specific primers and sequenced. The blast analysis revealed that the local field isolates of FPV showed 99 % homology with other FPV sequences available in the GenBank. The evidence for occurrence of feline panleukopenia infection in cats in Tamil Nadu, India was further confirmed by host specific nucleotides present in the VP2 gene region as well as virus isolation in A72 cell line.
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http://dx.doi.org/10.1007/s13337-014-0231-y | DOI Listing |
Mol Biol Rep
January 2025
College of Veterinary Medicine, Qingdao Agricultural University, Qingdao, 266109, PR China.
Background: Feline diarrhea is a common digestive tract disease in clinical practice, with watery feces as the main clinical manifestation. There are numerous pathogenic factors causing feline diarrhea, among which viral infections are prevalent, and feline panleukopenia virus (FPV) is the most common pathogen. In recent years, a variety of novel viruses have been detected in the intestines of cats with diarrhea.
View Article and Find Full Text PDFInfect Genet Evol
January 2025
Instituto Agroalimentario de Aragón-IA2 (Universidad de Zaragoza-CITA), Miguel Servet 177, 50013 Zaragoza, Spain; Fundación ARAID, Zaragoza, Av. Ranillas, 1-D, 50018 Zaragoza, Spain; Facultad de Ciencias de la Vida, Universidad Andres Bello, Av. República 252, Santiago, Chile. Electronic address:
Wild carnivorans are key hosts of parvoviruses of relevance for animal health and wildlife conservation. However, the distribution and diversity of parvoviruses among wild carnivorans are under-investigated, particularly in Southern Europe. We evaluated the presence, spread, and diversity of multi-host protoparvoviruses (canine parvovirus type 2 (CPV-2), feline panleukopenia virus (FPV)), and amdoparvoviruses in 12 carnivoran species from Northern Spain to explore viral ecology.
View Article and Find Full Text PDFViruses
December 2024
Key Laboratory of Veterinary Biological Engineering and Technology, Institute of Veterinary Medicine, Jiangsu Academy of Agricultural Sciences, Nanjing 210014, China.
The feline panleukopenia virus (FPV) is a highly contagious virus that affects cats worldwide, characterized by leukopenia, high temperature and diarrhea. Recently, the continuous prevalence and variation of FPV have attracted widespread concern. The aim of this study was to investigate the isolation, genetic evolution, molecular characterization and epidemiological analysis of FPV strains among cats and dogs in China from 2019 to 2024.
View Article and Find Full Text PDFAnimals (Basel)
December 2024
Department of Public Health, Faculty of Veterinary Medicine, "Ion Ionescu de la Brad" Iasi University of Life Sciences, Mihail Sadoveanu Alley, No. 8, 700489 Iasi, Romania.
Feline Panleukopenia (FPL) infection is caused by feline panleukopenia virus (FPV), and it is considered one of the most severe cat's infectious diseases. Since there is no specific antiviral treatment for FPL, the therapeutic protocol usually is focused on fluid therapy and supportive care. However, filgrastim, a granulocyte colony-stimulating factor (G-CSF) used in human medicine to treat neutropenia and leukopenia, has been lately used in treating FPV disease, providing promising results.
View Article and Find Full Text PDFMicroorganisms
October 2024
Department of Veterinary Medicine, College of Animal Science and Technology, Shihezi University, Shihezi 832000, China.
Feline panleukopenia virus (FPV), a globally pervasive and highly pathogenic pathogen, has garnered significant attention recently due to the cross-species transmission of its variants. Despite the vast body of research conducted on FPV, studies exploring its evolutionary history, dynamics, and the factors driving its evolution remain scarce. The pathogenicity of strains with the prevalent mutations (A91S and I101T) in the VP2 protein has also not been fully elucidated.
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