Drug information service was one of the first specialty areas of pharmacy practice. The importance of effectively searching, interpreting, and applying the medical literature continues today. The information systems that we use in today's health care environment have created new opportunities for pharmacists to apply their drug information expertise. We address some of these opportunities this month, along with a brief tie-in to work performed over a decade ago.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319809 | PMC |
http://dx.doi.org/10.1310/hpj4911-1081 | DOI Listing |
PeerJ
January 2025
Department of Field Crops, Aydin Adnan Menderes University, Aydin, Türkiye.
Background: Salinity stress is a significant challenge in agriculture, particularly in regions where soil salinity is increasing due to factors such as irrigation practices and climate change. This stress adversely affects plant growth, development, and yield, posing a threat to the cultivation of economically important plants like . This study aims to evaluate the effectiveness by proactively applying indole-3-butyric acid (IBA) to cuttings as a practical and efficient method for mitigating the adverse effects of salinity stress.
View Article and Find Full Text PDFZhongguo Zhong Yao Za Zhi
December 2024
Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences Beijing 100700, China.
This study aimed to investigate the potential role of Colquhounia Root Tablets against bone destruction in rheumatoid arthritis(RA) and its molecular mechanism. The study used ultra-performance liquid chromatography-mass spectrometry to analyze the major components of Colquhounia Root Tablets and predicted its candidate target gene set based on the major components. The key targets of RA bone destruction were obtained through GeneCards and the Database of Genetics and Medical Literature(OMIM), protein-protein interaction(PPI) network was constructed, and the key targets were identified by topological analysis.
View Article and Find Full Text PDFPeerJ
January 2025
Faculty of Agricultural Sciences, University of the Punjab, Lahore, Punjab, Pakistan.
The continuous contamination of heavy metals (HMs) in our ecosystem due to industrialization, urbanization and other anthropogenic activities has become a serious environmental constraint to successful crop production. Lead (Pb) toxicity causes ionic, oxidative and osmotic injuries which induce various morphological, physiological, metabolic and molecular abnormalities in plants. Polyethylene glycol (PEG) is widely used to elucidate drought stress induction and alleviation mechanisms in treated plants.
View Article and Find Full Text PDFSensors (Basel)
December 2024
School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, China.
Curcumae Longae Rhizoma (CLRh), Curcumae Radix (CRa), and Curcumae Rhizoma (CRh), derived from the different medicinal parts of the species, are blood-activating analgesics commonly used for promoting blood circulation and relieving pain. Due to their certain similarities in chemical composition and pharmacological effects, these three herbs exhibit a high risk associated with mixing and indiscriminate use. The diverse methods used for distinguishing the medicinal origins are complex, time-consuming, and limited to intraspecific differentiation, which are not suitable for rapid and systematic identification.
View Article and Find Full Text PDFNutrients
December 2024
Department of Pharmacognosy with Medicinal Plant Garden, Medical University in Lublin, 1 Chodzki St., 20-093 Lublin, Poland.
: We assessed the influence of long-term injection of magnoflorine (MAG) on memory acquisition in mice for the first time. : This isoquinoline alkaloid that belongs to the aporphines was isolated from the roots of by centrifugal partition chromatography (CPC) using a biphasic solvent system composed of chloroform: methanol: water in the ratio 4:3:3 (//) with 20 mM of hydrochloric acid and triethylamine, within 64 min. : Our results indicated that long-term injection of MAG 20 mg/kg dose improve the long-term memory acquisition in mice that were evaluated in the passive avoidance (PA) test with no toxicity records.
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