A mathematical model for the growth of solid avascular tumor with time delays in regulatory apoptosis is studied. The existence of stationary solutions and the mechanism of formation of necrotic cores in the growth of the tumors are studied. The results show that if the natural death rate of the tumor cell exceeds a fixed positive constant, then the dormant tumor is nonnecrotic; otherwise, the dormant tumor is necrotic.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211211 | PMC |
| http://dx.doi.org/10.1155/2014/467158 | DOI Listing |
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