The mammalian outer, middle, and inner ears have different embryonic origins and evolved at different times in the vertebrate lineage. The outer ear is derived from first and second branchial arch ectoderm and mesoderm, the middle ear ossicles are derived from neural crest mesenchymal cells that invade the first and second branchial arches, whereas the inner ear and its associated vestibule-acoustic (VIIIth) ganglion are derived from the otic placode. In this chapter, we discuss recent findings in the development of these structures and describe the contributions of members of a Forkhead transcription factor family, the Foxi family to their formation. Foxi transcription factors are critical for formation of the otic placode, survival of the branchial arch neural crest, and developmental remodeling of the branchial arch ectoderm.
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http://dx.doi.org/10.1016/bs.ctdb.2014.11.014 | DOI Listing |
Int J Surg Case Rep
January 2025
King Edward Medical University Lahore, Pakistan.
Introduction And Importance: The branchial or pharyngeal apparatus, crucial in embryological development, consists of clefts, arches, pouches, and membranes. Anomalies arising from this apparatus particularly involving the second branchial arch, are rare. Among these anomalies, complete second branchial cleft fistulas, with both external and internal openings, are exceptionally uncommon.
View Article and Find Full Text PDFInt J Pediatr Otorhinolaryngol
January 2025
Department of Clinical and Experimental Medicine, Section of Pediatrics and Child Neuropsychiatry, Hospital "Policlinico G. Rodolico", Catania, Italy. Electronic address:
Acute suppurative thyroiditis (AST), a rare yet potentially life-threatening infection, comprises less than 1 % of neck pathologies and requires prompt treatment. Symptoms range from neck pain and fever to dysphagia and possible abscess formation. Broad-spectrum antibiotics are the primary treatment; however, surgical drainage may be necessary for abscesses to prevent systemic infection.
View Article and Find Full Text PDFDev Biol
March 2025
Stowers Institute for Medical Research, USA; Children's Mercy Hospital/Children's Mercy Research Institute, USA. Electronic address:
A core framework of the gene regulatory network (GRN) governing neural crest (NC) cell development has been generated by integrating separate inputs from diverse model organisms rather than direct comparison. This has limited insights into the diversity of genes in the NC cell GRN and extent of conservation of newly identified transcriptional signatures in cell differentiation and invasion. Here, we address this by leveraging the strengths and accessibility of the avian embryo to precise developmental staging by egg incubation and use an integrated analysis of chick (HH13) and mouse (E9.
View Article and Find Full Text PDFMicrosc Res Tech
December 2024
Higher Institution Centre of Excellence (HICoE), Institute of Tropical Aquaculture and Fisheries, Universiti Malaysia Terengganu, Kuala Nerus, Terengganu, Malaysia.
The Y-organs (YOs) synthesize and secrete molting hormones, and thus regulate crustacean growth and reproduction. However, the YOs of the orange mud crab Scylla olivacea is yet to be described due to its minute size and ambiguous feature. This study describes the location, morphological characteristics, histology, and the changes of YOs at different molt stages, and examines in vitro ecdysteroid secreted by the YOs of S.
View Article and Find Full Text PDFZookeys
December 2024
Department of Oceanography, National Sun Yat-sen University, Kaohsiung, Taiwan.
A new species of beardfish, genus , is described based on three specimens collected in Taiwanese waters and off the Chesterfield Islands of New Caledonia. It can be distinguished from its congeners by the following characters: dorsal-fin rays IV-V, 35-37; gill rakers on outer face of first gill arch 3+1+6=10; scales row between dorsal-fin origin and lateral line vertically 6-8 (S1) and posteriorly 12-14 (S2); pyloric caeca 40; snout rounded, with its surface rough and gelatinous, its tip evidently protrude anterior margin of premaxilla; ctenii on body scales arranged in a wedge-shape, forming three rows; 4 anal-fin spine long, 1.0%-1.
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