AI Article Synopsis

  • The study aimed to determine if the age at which spontaneous resolution of monosymptomatic nocturnal enuresis (MNE) occurs is influenced by family history.
  • Researchers surveyed over 1,500 people and identified 100 participants with MNE and a familial history of MNE resolution, analyzing the correlation between parents' and children's resolution ages.
  • Results indicated a positive correlation between the ages of resolution in participants and their parents, suggesting a familial link, while other factors like gender and parental education did not show significant effects.

Article Abstract

Purpose: To investigate whether or not the age of spontaneous resolution of monosymptomatic nocturnal enuresis (MNE) was familial.

Patients And Methods: A questionnaire was administered to more than 1,500 people, and 100 appropriate participants were identified from four referral hospitals. We included the participants who had MNE and whose parents also had MNE with spontaneous resolution. Then the association between the spontaneous resolution time of MNE in parents and that in their children was investigated.

Results: The mean ages of spontaneous resolution were 10.7 (10-30 years), 9.4 (6-17 years) and 10.9 (6-18 years) in participants, their mothers and their fathers, respectively. According to the statistical analysis, there was a positive correlation between participants and both their mothers and fathers (p < 0.05). In addition, it was revealed that familial MNE history based on first- and second-degree relatives, in addition to their parents, was also associated with the increased spontaneous resolution age of MNE (p < 0.05). According to our results, gender and parents' education status were not statistically associated with the spontaneous resolution (p > 0.05).

Conclusion: As a conclusion, the age of spontaneous resolution of MNE is familial. Although the exact reasons of spontaneous resolution still remain a mystery; further genetic investigations may be able to resolve this mystery.

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Source
http://dx.doi.org/10.1159/000370166DOI Listing

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