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Management of Osteoporosis in Parkinson's Disease: A Systematic Review of Clinical Practice Guidelines.
Mov Disord Clin Pract
December 2024
Department of Medicine, School of Clinical Sciences at Monash Health, Faculty of Medicine, Monash Medical Centre, Nursing and Health Sciences, Monash University, Clayton, Victoria, Australia.
Background: Parkinson's disease (PD) is the fastest-growing neurological disorder globally. Defining features include tremor, muscular rigidity, bradykinesia, and postural instability, which in combination with nonmotor symptoms such as cognitive impairment and orthostatic hypotension increase the risk of falls. Along with low bone mineral density, fracture risk is high in PD.
View Article and Find Full Text PDFThalamic Local Field Potentials and Closed-Loop Deep Brain Stimulation in Orthostatic Tremor.
Mov Disord
October 2024
Edmond J. Safra Program in Parkinson's Disease and Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, UHN, Toronto, Ontario, Canada.
Background: Orthostatic tremor (OT) is a rare movement disorder characterized by a feeling of unsteadiness and a high-frequency tremor in the legs (13-18 Hz) relieved by sitting or walking.
Objectives: The aims were to study the brain electrophysiology captured chronically in a person with medication-refractory OT while standing and walking and in the semi-recumbent position using bilateral ventral intermedius nucleus deep brain stimulation (DBS) (Medtronic Percept PC) and to describe the clinical use of closed-loop DBS.
Methods: A sensing survey was used to capture baseline local field potentials (LFPs) while standing.
Three hertz orthostatic tremor as "red flag sign" candidate for multiple system atrophy.
Neurol Sci
September 2024
Institute for Brain Research and Rehabilitation, South China Normal University, Guangzhou, China.
Aim: This study investigates the potential of 3-Hz orthostatic tremor (OT) as a diagnostic red-flag sign for differentiating multiple system atrophy (MSA) from Parkinson's disease (PD).
Patients And Methods: A total of 615 PD patients and 234 MSA patients (120 MSA-P and 114 MSA-C) participated. OT at ~ 3 Hz and other frequencies was identified through rhythmic postural sway on the stabilogram map and confirmed by fast Fourier transform (FFT) analysis.
Movement Disorders in Brain Sagging Syndrome Due To Spontaneous Intracranial Hypotension: A Review.
Tremor Other Hyperkinet Mov (N Y)
September 2024
Department of Neurology, University of Texas Southwestern Medical Center, Dallas, TX, US.
Background: Spontaneous intracranial hypotension (SIH), a treatable condition that stems from spinal leakage of cerebrospinal fluid, usually presents with orthostatic headache, nausea, vomiting, dizziness, and tinnitus. A subset of patients, especially those with sagging of brain structures ("brain sagging syndrome"), develop several movement abnormalities. As SIH is treatable with epidural blood patch (EBP), movement disorders neurologists should be familiar with this syndrome.
View Article and Find Full Text PDFPseudo-Orthostatic Tremor in Graves' Disease: A Possible Early Sign of Parkinsonism?
Tremor Other Hyperkinet Mov (N Y)
July 2024
Department of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy.
Background: Pseudo-orthostatic tremor is a hyperkinetic movement disorder usually associated with other neurological comorbidities, mainly Parkinson's disease.
Case Report: A 65-year-old male presented with unsteadiness and leg tremor while standing. Electrophysiological evaluation confirmed the presence of pseudo-orthostatic tremor.
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