Scaling up an electrochemical signal with a catalytic hairpin assembly coupling nanocatalyst label for DNA detection.

Chem Commun (Camb)

Key Laboratory of Sensor Analysis of Tumor Marker, Ministry of Education, Shandong Provincial Key Laboratory Of Biochemical Analysis, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, China.

Published: April 2015

A strategy for the electrochemical detection of DNA based on catalytic hairpin assembly combined with nanocatalyst label-based redox cycling reaction signal amplification. A superior detection limit of 0.3 aM toward DNA can be achieved.

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http://dx.doi.org/10.1039/c5cc00680eDOI Listing

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