We report a rare case of anaphylaxis due to caffeine intake. A 27-year-old woman suffered her first episode of anaphylaxis and a positive skin prick test suggested that the anaphylaxis was due to an IgE-mediated hypersensitivity reaction to caffeine. She was diagnosed with caffeine allergy and has not had an allergic reaction after avoiding foods and drinks containing caffeine. Although caffeine is known to have antiallergic effects, this case shows that caffeine can be an allergen and cause anaphylaxis.
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http://dx.doi.org/10.5415/apallergy.2015.5.1.55 | DOI Listing |
Int J Pharm
October 2023
Department of Pharmacology, The Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Department of Medicine, University of Pennsylvania, Philadelphia, PA, USA. Electronic address:
Infusion reactions are a major risk for advanced therapeutics (e.g., engineered proteins nanoparticles, etc.
View Article and Find Full Text PDFClin Mol Allergy
December 2021
School of Nursing, Miyagi University, 1-1 Gakuen, Taiwa-cho, Kurokawa-gun, Miyagi, 981-3298, Japan.
To fight against coronavirus disease 2019 (COVID-19), the vaccination is currently the most effective approach. However, in addition to common systemic side effects, the vaccines can cause serious allergic reactions or anaphylaxis. In anaphylaxis, the exposure to the allergen causes a sudden release of chemical mediators from mast cells, for which adrenaline is the drug of first choice.
View Article and Find Full Text PDFEur J Pharm Biopharm
December 2020
Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Dermatology Venereology and Allergology, Center of Experimental and Applied Cutaneous Physiology, Charité Universitätsmedizin Berlin, Germany.
The aim of this study was to develop an ex vivo method that allows to quantify the transfollicular penetration of topically applied substances by combining microdialysis and selective follicular closure with varnish. An experimental setup with three skin areas on ex vivo intact porcine ear skin was designed (varnish on hair follicle, varnish next to hair follicle, no varnish). On each area, 10 µl/cm caffeine-hydroxyethyl-cellulose-gel was applied.
View Article and Find Full Text PDFFP Essent
September 2018
Florida Hospital Family Medicine Residency, 133 Benmore Drive, Winter Park, FL 32792.
Food allergies are immune-mediated allergic adverse reactions that occur after exposure to specific foods. The most commonly recognized food allergies are immunoglobulin E (IgE)-mediated reactions (eg, urticaria, angioedema, anaphylaxis) that result from exposure to milk, egg, peanut, tree nuts, shellfish, fish, wheat, or soy. However, other foods can cause food allergies.
View Article and Find Full Text PDFAsia Pac Allergy
January 2015
Department of Respiratory Medicine, Dokkyo Medical University Koshigaya Hospital, Koshigaya 343-8555, Japan. ; Department of Pulmonary Medicine and Clinical Immunology, Dokkyo Medical University, Mibu 321-0293, Japan.
We report a rare case of anaphylaxis due to caffeine intake. A 27-year-old woman suffered her first episode of anaphylaxis and a positive skin prick test suggested that the anaphylaxis was due to an IgE-mediated hypersensitivity reaction to caffeine. She was diagnosed with caffeine allergy and has not had an allergic reaction after avoiding foods and drinks containing caffeine.
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