Infected pancreatic necrosis is a challenging complication that worsens prognosis in acute pancreatitis. For years, open necrosectomy has been the mainstay treatment option in infected pancreatic necrosis, although surgical debridement still results in high morbidity and mortality rates. Recently, many reports on minimally invasive treatment in infected pancreatic necrosis have been published. This paper presents a review of minimally invasive techniques and attempts to define their role in the management of infected pancreatic necrosis.
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http://dx.doi.org/10.5114/pg.2014.47893 | DOI Listing |
Cancer Med
January 2025
Interface Demography, Department of Sociology, Vrije Universiteit Brussel, Brussels, Belgium.
Background: The COVID-19 pandemic disrupted global health systems, impacting cancer care and potentially increasing cancer mortality, especially among socioeconomically disadvantaged individuals. We aimed to assess changes in cancer mortality from March 1 to December 31, 2020 relative to the same period in 2019, and to examine potential shifts in cancer mortality's social disparities during the same time frame.
Methods: We used nationwide individually linked cancer mortality data from the Belgian National Register, the Census 2011, and the tax register.
Biomed Rep
February 2025
Department of Medical Laboratory Sciences, Faculty of Allied Medical Sciences, Al-Balqa Applied University, Al-Salt 19117, Jordan.
Silver nanoparticles (AgNPs) are spherical particles with a number of specific and unique physical (such as surface plasmon resonance, high electrical conductivity and thermal stability) as well as chemical (including antimicrobial activity, catalytic efficiency and the ability to form conjugates with biomolecules) properties. These properties allow AgNPs to exhibit desired interactions with the biological system and make them prospective candidates for use in antibacterial and anticancer activities. AgNPs have a quenching capacity, which produces reactive oxygen species and disrupts cellular processes (such as reducing the function of the mitochondria, damaging the cell membrane, inhibiting DNA replication and altering protein synthesis).
View Article and Find Full Text PDFEur J Med Res
January 2025
Department of Emergency, Huzhou Central Hospital, Affiliated Central Hospital of Huzhou University, No. 1558, Sanhuan North Road, Wuxing District, Huzhou, 313000, People's Republic of China.
Background: Elderly acute kidney injury (AKI) occurring in the intensive care unit (ICU), particularly when caused or accompanied by sepsis, is linked to extended hospital stays, increased mortality rates, heightened prevalence of chronic diseases, and diminished quality of life. This study primarily utilizes a comprehensive critical care database to examine the correlation of albumin corrected anion gap (ACAG) levels with short-term prognosis in elderly patients with AKI caused or accompanied by sepsis, thus assisting physicians in early identification of high-risk patients.
Methods: This study utilized data from the Medical Information Mart for Intensive Care IV (MIMIC-IV, v2.
Viruses
November 2024
Department of Biological Sciences, University of Alabama, Tuscaloosa, AL 35487, USA.
Unlabelled: Di(2-ethhylhexyl) phthalate (DEHP) is a common plastic rubberizer. DEHP leaches from plastic matrices and is under increasing scrutiny as numerous studies have linked it to negative human health manifestations. Coxsackievirus B3 (CVB) is a human pathogen that typically causes subclinical infections but can sometimes cause severe diseases such as pancreatitis, myocarditis, and meningoencephalitis.
View Article and Find Full Text PDFMedicina (Kaunas)
November 2024
Regional Institute of Gastroenterology and Hepatology "Octavian Fodor", 400394 Cluj-Napoca, Romania.
: This study evaluated the impact of the COVID-19 pandemic on the surgical management of pancreatic ductal adenocarcinoma (PDAC) at a tertiary care hospital in Romania. The objective was to compare surgical volumes, tumor characteristics, and patient outcomes across three periods: pre-COVID, pandemic, and post-COVID. : A retrospective analysis of 622 PDAC patients who underwent surgery between February 2018 and February 2024 was conducted.
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