AI Article Synopsis
- - Bacillary angiomatosis (BA) is a condition where new blood vessels grow abnormally in the skin and other organs of immunosuppressed individuals, primarily caused by Bartonella bacteria, notably affecting those with HIV.
- - Diagnosis involves blood tests, bacterial cultures, and techniques like PCR to find Bartonella DNA in tissue samples.
- - A significant case was reported involving a renal transplant patient, highlighting the importance of considering BA in immunocompromised patients who show symptoms like fever and skin lesions that resemble angiomas.
Article Abstract
Bacillary angiomatosis (BA) is a disorder of neovascular proliferation involving skin and other organs of immunosuppressed patients caused by Bartonella species. BA has been recognized in both immunocompetent and immunodeficient patients, mostly in human immunodeficiency virus (HIV)-infected persons, much more rare in those with other immunodeficiencies, including organ transplantation. Diagnosis is based on serologic analysis, culture and molecular biology [detection of Bartonella species deoxyribonucleic acid (DNA) in tissue biopsy extracts by real-time polymerase chain reaction (PCR)]. All immunosuppressed patients with BA should be treated with antibiotics because of potentially life-threatening course of the disease. We report the first case of cutaneous bacillary angiomatosis due to Bartonella quintana in renal transplant recipient. This presentation demonstrates that BA should be considered a differential diagnosis in immunocompromised patients presenting with fever and cutaneous angioma-like lesions.
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| http://dx.doi.org/10.1111/tri.12539 | DOI Listing |
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A 34-year-old male patient presented with a clinical picture of multilocular subcutaneous skin nodules in addition to marked lymphadenopathy and general physical deterioration. A comprehensive diagnostic workup including serology, skin biopsy and imaging studies led to the initial diagnosis of human immunodeficiency virus (HIV) infection in AIDS stage with rare multilocular subcutaneous bacillary angiomatosis (BA) caused by Bartonella henselae. BA describes a process of neovascularisation of the skin or of internal organs (particularly the liver and spleen) and was first described in HIV-positive patients by Stoler et al.
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