To study the effects of clinicians' slow rate on the speech of children who stutter with and without a concomitant phonological disorder, an A-B-A-B single case design was used with six clinician-child dyads, where B = Clinician's slow speech rate model. Two boys and one girl, aged 49-54 months, stuttering with disordered phonology (S + DP), were compared to three boys aged 42-50 months, stuttering with normal phonology (S + NP). Articulation rates were measured in phones per second (pps) in clinician-child adjacent utterance pairs. The S + NP dyads showed improved fluency in the B condition through a larger effect size, higher mean baseline stutter reductions and lower percentages of non-overlapping data than did the S + DP dyads. The S + DP girl showed relatively improved fluency in the B condition. S + DP children showed no articulation rate alignment (Range: 16% decrease to a 1.2% increase), whereas S + NP children averaged a 20% pps rate reduction (Range: 19.6-25.4% decrease), aligning with their clinicians who averaged a 38% pps rate reduction from baseline. The S + DP group spoke significantly (z = -4.63; p < 0.00) slower at baseline (Mdn = 6.9 pps; SE = 0.07 pps) than S + NP children in previously published samples (Mdn = 9.8 pps; SE = 0.22 pps). Results suggest that a slow rate model alone is not effective for facilitating fluency in S + DP boys with time since onset of about 2 years.
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http://dx.doi.org/10.3109/02699206.2014.1003970 | DOI Listing |
J Commun Disord
December 2024
MRC Cognition and Brain Sciences Unit, University of Cambridge, Cambridge, UK.
Objectives: The objectives of this study were to evaluate the relationships between auditory processing, speech discrimination, and listening and communication abilities in children diagnosed with auditory neuropathy spectrum disorder (ANSD) compared to those with normal hearing.
Methods: This was a case-control study involving seventeen participants with a diagnosis of ANSD who used spoken language as their primary mode of communication and wore hearing aids or were unaided and 21 normally hearing controls. All underwent a battery of behavioural measures of hearing, speech perception and auditory processing skills.
J Neurosci
January 2025
Neuroscience and Cognitive Science Program, University of Maryland, College Park, Maryland, 20742.
Hearing is an active process in which listeners must detect and identify sounds, segregate and discriminate stimulus features, and extract their behavioral relevance. Adaptive changes in sound detection can emerge rapidly, during sudden shifts in acoustic or environmental context, or more slowly as a result of practice. Although we know that context- and learning-dependent changes in the sensitivity of auditory cortical (ACX) neurons support many aspects of perceptual plasticity, the contribution of subcortical auditory regions to this process is less understood.
View Article and Find Full Text PDFInt J Emerg Med
December 2024
Mejiro University Ear Institute Clinic, 320 Ukiya, Iwatsuki-ku, Saitama-shi, Saitama, 339-8501, Japan.
Background: Reduction of spontaneous nystagmus by fixation, a characteristic feature of peripheral nystagmus, is important for differentiating between peripheral and central vestibular disorders. In the emergency room, Frenzel goggles are recommended to observe spontaneous nystagmus for the differential diagnosis of acute vestibular syndrome. We developed a portable loupe with a Fresnel lens to observe nystagmus.
View Article and Find Full Text PDFEur J Med Genet
December 2024
First Department of Neurology, First Affiliated Hospital of Kunming Medical University, Kunming, 650000, China. Electronic address:
The Chromodomain Helicase DNA-binding (CHD) protein family is ATP-dependent chromatin remodeling proteins that utilize energy produced by ATP hydrolysis to regulate chromatin structure and thereby modulate gene expression. The earliest report of a CHD3 gene mutation was by O'Roak, who found it during whole exome sequencing of 189 autism families in 2012. In 2018, Snijders Blok systematically assessed the autosomal dominant neurodevelopmental disorder caused by CHD3 gene damage, known as Snijders Blok-Campeau syndrome (SNIBCPS, OMIM 618205).
View Article and Find Full Text PDFCereb Cortex
December 2024
Instituto de Investigaciones Biológicas Clemente Estable, Department of Integrative and Computational Neurosciences, Av. Italia 3318, Montevideo, 11.600, Uruguay.
A social scene is particularly informative when people are distinguishable. To understand somebody amid a "cocktail party" chatter, we automatically index their voice. This ability is underpinned by parallel processing of vocal spectral contours from speech sounds, but it has not yet been established how this occurs in the brain's cortex.
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