This study is aimed at evaluating the association between occupational exposure to organophosphate (OP) and carbamate (CB) pesticides and semen quality as well as levels of reproductive and thyroid hormones of pesticide sprayers in Malihabad, Lucknow, Uttar Pradesh, India. Thirty-five healthy men (unexposed group) and 64 male pesticide sprayers (exposed group) were recruited for clinical evaluation of fertility status. Fresh semen samples were evaluated for sperm quality and analyzed for DNA fragmentation index (DFI) by flow cytometry. Pesticide exposure was assessed by measuring erythrocyte acetylcholinesterase and plasma butyrylcholinesterase (BuChE) with a Test-mate ChE field kit. Serum levels of total testosterone (Tt), prolactin (PRL), follicle-stimulating hormone (FSH), luteinizing hormone (LH), thyroid-stimulating hormone (TSH), and free thyroxine (FT4) were analyzed using enzyme immunoassay kits. Evidence of pesticide exposure was found in 88.5% of sprayers and significant increments were observed in sperm DFI with significant decrease in some semen parameters. DFI was negatively correlated with BuChE, sperm concentration, morphology, and vitality in these pesticide sprayers. The levels of Tt, PRL, FT4, and TSH appeared to be normal; however, there was a tendency for increased LH and FSH levels in exposed workers. The results confirm the potential impact of chronic occupational exposure to OP and CB pesticides on male reproductive function, which may cause damage to sperm chromatin, decrease semen quality, and produce alterations in reproductive hormones, leading to adverse reproductive health outcomes.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1177/0748233714568175 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Development and assessment of a novel single-drive variable angle spraying machine.
Sci Rep
December 2024
School of Mechanical Engineering, Changzhou Institute of Technology, Changzhou, 213032, China.
Traditional sprayers are limited to applying spray mixture solely to the upper surfaces of crops. To overcome this limitation, a variable angle spraying machine (VASM) was designed using a linkage system. This machine enables the adjustment of both the spray position and angle through a single input signal, facilitating multi-directional spraying from the top to the bottom of crops.
View Article and Find Full Text PDFEffect of pesticide application techniques on thrips control in the cowpea flowering stage.
Pest Manag Sci
December 2024
College of Science, China Agricultural University, Beijing, China.
Background: Thrips are among the most damaging pests to cowpeas in Hainan, China. Conventional pesticide application methods often fail to achieve satisfactory control due to the small size and concealed habitats of thrips. This study aimed to enhance the efficacy of pesticides by improving their application techniques.
View Article and Find Full Text PDFDesign and regulation as a chain of determinants in the emergence of pesticide exposure situations during the use of sprayers.
Ergonomics
December 2024
Bordeaux Population Health Research Center, INSERM U1219, University of Bordeaux, Bordeaux, France.
Our study was carried out in winegrowing in France and relates to the prevention of pesticide exposure situations. During treatments, the sprayer is a technical determinant directly responsible for these situations because of its design. The objective of our study is to gain a better understanding of pesticide exposure situations during the use of sprayers, by identifying the design of these machinery and the regulations that apply to it as a chain of determinants.
View Article and Find Full Text PDFEffect of vitamin supplementation and exposure-free break on hematological, Biochemical, and pathological parameters in male Wistar rats exposed to quinalphos.
J Family Med Prim Care
October 2024
Department of Pharmacology, SVMCH & RC, Pondicherry, India.
Article Synopsis
- India relies heavily on cash crop agriculture, leading to widespread pesticide use that poses significant public health risks due to chronic exposure among various workers.
- The study focuses on the effects of the organophosphorus pesticide quinalphos, known to cause oxidative damage in vital organs, and investigates the potential protective effects of vitamins E and C.
- 24 male Wistar rats were divided into four groups to assess the impact of quinalphos exposure and vitamin supplementation on blood count, antioxidant enzymes, liver enzymes, and histopathological changes after 60 days.
[Molluscicidal effect of spraying 5% niclosamide ethanolamine salt granules with drones against in marshland areas].
Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi
October 2024
National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research), National Health Commission Key Laboratory of Parasite and Vector Biology, WHO Collaborating Centre for Tropical Diseases, National Center for International Research on Tropical Diseases, Ministry of Science and Technology, Shanghai 200025, China.
Article Synopsis
- The study aimed to assess the effectiveness of using 5% niclosamide ethanolamine salt granules, applied with drones, for controlling snail populations in marshland habitats.
- Four experimental groups were created, with variations in environmental cleaning and application methods, to monitor snail mortality and density over a two-week period.
- Results showed varying mortality rates among groups, with the highest in the groups that employed environmental cleaning, indicating that pre-treatment cleaning is beneficial for improving the molluscicidal effect.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!