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From formamide to RNA, the path is tenuous but continuous. | LitMetric

From formamide to RNA, the path is tenuous but continuous.

Life (Basel)

Fondazione "Istituto Pasteur-Fondazione Cenci-Bolognetti" c/o Dipartimento di Biologia e Biotecnologie "Charles Darwin", "Sapienza" Università di Roma, P.le Aldo Moro, 5, 00185 Rome, Italy.

Published: January 2015

Reactions of formamide (NH2COH) in the presence of catalysts of both terrestrial and meteoritic origin yield, in plausible and variegated conditions, a large panel of precursors of (pre)genetic and (pre)metabolic interest. Formamide chemistry potentially satisfies all of the steps from the very initial precursors to RNA. Water chemistry enters the scene in RNA non-enzymatic synthesis and recombination.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4390857PMC
http://dx.doi.org/10.3390/life5010372DOI Listing

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