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An unusual case of reagent interference in transfusion medicine workup: Pan reactive indirect antiglobulin test caused by commercial saline solution.
Transfus Med
November 2024
Department of Clinical Immunology, Odense University Hospital, Odense, Denmark.
Background: At the regional transfusion service in the Region of Southern Denmark, serological investigations are primarily carried out using column agglutination techniques. This case study examines an unusual instance of reagent interference in pretransfusion testing using column agglutination at the Hospital of Southern Denmark, Aabenraa.
Case Presentation: A 72-year-old male patient presented for pretransfusion testing prior to hernia surgery.
Bayesian accuracy estimates for diagnostic tests to detect tuberculosis in captive sun bears (Helarctos malayanus) and Asiatic black bears (Ursus thibetanus) in Cambodia and Vietnam.
PLoS One
November 2024
School of Veterinary Medicine, Murdoch University, Perth, WA, Australia.
Effective control of tuberculosis (TB) depends on early diagnosis of disease, yet available tests are unable to perfectly detect infected individuals. In novel hosts diagnostic testing methods for TB are extrapolated from other species, with unknown accuracy. The primary challenge to evaluating the accuracy of TB tests is the lack of a perfect reference test.
View Article and Find Full Text PDF[Genetic analysis of a blood donor with combined FUT1 and ABO dual blood group gene variants resulting in para-Bombay and A2 subtype blood types and a literature review].
Zhonghua Yi Xue Yi Chuan Xue Za Zhi
November 2024
Blood Transfusion Institute, Zhejiang Blood Center, Hangzhou, Zhejiang 310052, China.
Objective: To investigate the serological and molecular genetic characteristics of a voluntary blood donor with combined FUT1 and ABO blood group gene variants causing para-Bombay and A2 subtype, and to review relevant literature on para-Bombay blood types carrying alleles such as FUT101W.37 and FUT101W.23.
View Article and Find Full Text PDFA phenotype associated with novel ABO*A allele variant c.106delinsGG.
Asian J Transfus Sci
June 2024
Red Cell Reference Laboratory, Pathology and Clinical Governance, Australian Red Cross Lifeblood, Brisbane, Australia.
Background And Objectives: Discrepancy between forward and reverse ABO grouping could be due to several reasons including genetic mutations of the alleles encoding group specific transferase. The healthy donors found with weak A antigen were investigated to ascertain the allele responsible for variation.
Materials And Methods: Standard serological methods were employed using commercial antisera.
A Case of Weak D Serologic Phenotype.
WMJ
February 2024
Medical College of Wisconsin, Fox Valley Family Medicine Residency, Appleton, Wisconsin.
Introduction: Rh D alloimmunization is the serologic response that occurs when Rh D-negative patients are exposed to Rh D-positive blood. Rh D blood typing is recommended in pregnancy to prevent alloimmunization.
Case Presentation: A 27-year-old gravida 3, para 2012 (G3P2012) previously Rh D-negative female presented with discordant and weakly positive Rh D blood typing results.
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