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Carvone-loaded chitosan nanoparticles alleviate joint destruction by downregulating the expression of pro, inflammatory cytokines and MMP-13 in adjuvant-induced rat model.
Inflammopharmacology
December 2024
Institute of Microbiology, University of Agriculture, Faisalabad, Pakistan.
Rheumatoid arthritis is an autoimmune illness causing deformity, edema, and joint tenderness. Its long-term treatment burdens the healthcare system and leads to toxicity, and thus, finding safe, effective, and affordable therapies is essential. The current study aimed to exhibit the anti-arthritic activity of Carvone-loaded chitosan nanoparticles to treat Freund's complete adjuvant (FCA) arthritis in rats.
View Article and Find Full Text PDFAgeism and Ableism in Individuals Aging with Intellectual and Developmental Disabilities.
Dent Clin North Am
January 2025
Geriatric Dentistry, University of Maryland School of Dentistry, 650 West Baltimore Street #3211, Baltimore, MD 21201, USA. Electronic address:
Biomedical and structural factors impact oral health for people with intellectual and developmental disabilities (IDD). The onset of age prevalent chronic diseases and conditions can result in new cognitive or physical disabilities leaving individuals with IDD to contend with ageism as well as ableism and further exclusion from the oral health care systems. Environments and attitudes that inform how health care systems are built and maintained significantly impact quality of life and outcomes, more than the fact of being disabled or old.
View Article and Find Full Text PDFSpecialty choices among new generation of doctors - insights from a Polish survey study.
Sci Rep
November 2024
Department of Health Policy and Management, Institute of Public Health, Faculty of Health Sciences, Jagiellonian University Medical College, Kraków, Poland.
The choice of medical specialty for future doctors is a multidimensional issue, associated with many factors. This study aimed to explore the factors influencing the specialty choices of doctors entering the Polish healthcare system. A nationwide cross-sectional survey was conducted from May until August 2023.
View Article and Find Full Text PDFArticle Synopsis
- * Recent efforts to stop smoking haven't been put into action yet, and it’s important to see what could happen if smoking rates stay the same or improve.
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- Researchers studied strokes from 1990 to 2021 to understand how many people get them and how they are affected around the world.
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