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Background: The pathogenesis of colorectal cancer (CRC) is influenced by various risk factors, and genetic alterations in progression of colon polyps. The expression patterns of microRNA-548 (miR-548) in colorectal tissues have been sufficiently characterized. The aim of this study is to clarify the role of miR-548aa in tumorigenesis, gene targeting, predictive value and its expression levels in tumoral versus adjacent marginal tissues in CRC patients.
View Article and Find Full Text PDFBiomarkers in Atopic Dermatitis: A Review of the Role of IL-13 and the Impact of Tralokinumab Treatment.
Am J Clin Dermatol
January 2025
David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
Atopic dermatitis (AD) is a chronic, inflammatory skin disease that can significantly affect quality of life. Presence, severity, and therapeutic response of AD are traditionally reported through clinical assessments including the Eczema Area and Severity Index or Investigator's Global Assessment. These clinical rating scales are visual assessments used in clinical trials to denotate AD severity.
View Article and Find Full Text PDFThe role of cerebellum in controlling eye movements is well established, but its contribution to more complex forms of visual behavior has remained elusive. To study cerebellar activity during visual attention we recorded extracellular activity of dentate nucleus (DN) neurons in two non-human primates (NHPs). NHPs were trained to read the direction indicated by a peripheral visual stimulus while maintaining fixation at the center, and report the direction of the cue by performing a saccadic eye movement into the same direction following a delay.
View Article and Find Full Text PDFReducing reading time and assessing disease in capsule endoscopy videos: A deep learning approach.
Int J Med Inform
January 2025
University of Coimbra, Faculty of Medicine, Coimbra, Portugal; Department of Gastroenterology, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal. Electronic address:
Background: The wireless capsule endoscope (CE) is a valuable diagnostic tool in gastroenterology, offering a safe and minimally invasive visualization of the gastrointestinal tract. One of the few drawbacks identified by the gastroenterology community is the time-consuming task of analyzing CE videos.
Objectives: This article investigates the feasibility of a computer-aided diagnostic method to speed up CE video analysis.
Relationship between the learning gains and learning style preferences among students from the school of medicine and health sciences.
BMC Med Educ
January 2025
Laboratorio de Inmunofarmacología, Instituto Nacional de Enfermedades Respiratorias, Calzada de Tlalpan 4502, Colonia Sección XVI, CP 14080, Mexico, México.
Background: The field of health sciences is constantly evolving, presenting significant challenges to student learning performance. Therefore, it is crucial to identify the factors influencing students' learning style preferences, as these relate to how they acquire, understand, interpret, organize, and process information from their courses. In this study, we evaluated whether there is a relationship between students' learning style preferences and their learning gains.
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