AI Article Synopsis
- A new eco-friendly method to synthesize benzopyrazines and bis-benzopyrazines using diamines and dicarbonyl compounds in water with indium powder as a catalyst under microwave conditions has been developed.
- The researchers explored the effects of microwave power and temperature to optimize the reaction for the best results.
- This microwave method offers higher efficiency and better yields compared to traditional methods, making it a more sustainable approach in organic synthesis.
Article Abstract
A convenient green synthesis of benzopyrazines and bis-benzopyrazines has been performed by the condensation of diversely substituted diamines and dicarbonyl compounds in water using indium powder as catalyst under controlled microwave exposure. The effects of microwave power, and temperature on this reaction are investigated in detail to identify the best condition. A wide range of diversely substituted diamines and dicarbonyl compounds produce excellent yield of the corresponding benzopyrazines and bis-benzopyrazines. A comparative study has also been made between microwave-induced procedure and conventional method. The present method is atom-economical, environmentally friendly, and affords synthetically useful and challenging products very rapidly.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.2174/1386207318666150131125053 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
A selective, expeditious and sustainable entry en route to benzopyrazines and bis-benzopyrazines.
Comb Chem High Throughput Screen
September 2015
Department of Chemistry, The University of Texas-Pan American, 1201 West University Drive, Edinburg, Texas 78539, USA.
Article Synopsis
- A new eco-friendly method to synthesize benzopyrazines and bis-benzopyrazines using diamines and dicarbonyl compounds in water with indium powder as a catalyst under microwave conditions has been developed.
- The researchers explored the effects of microwave power and temperature to optimize the reaction for the best results.
- This microwave method offers higher efficiency and better yields compared to traditional methods, making it a more sustainable approach in organic synthesis.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!