Systems biology of polycystic kidney disease: a critical review.

Wiley Interdiscip Rev Syst Biol Med

Kidney Disease Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA.

Published: November 2015

The proliferation and diminishing costs of 'omics' approaches have finally opened the doors for small and medium laboratories to enter the 'systems biology era'. This is a welcome evolution that requires a new framework to design, interpret, and validate studies. Here, we highlight some of the challenges, contributions, and prospects of the 'cyst-ems biology' of polycystic kidney disease.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4339620PMC
http://dx.doi.org/10.1002/wsbm.1289DOI Listing

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