Background: Pregnancy in women with autoimmune rheumatic diseases is associated with several maternal and fetal complications. The development of clinical practice guidelines with the best available scientific evidence may help standardize the care of these patients.
Objectives: To provide recommendations regarding prenatal care, treatment, and a more effective monitoring of pregnancy in women with lupus erythematosus (SLE), rheumatoid arthritis (RA) and antiphospholipid antibody syndrome (APS).
Methodology: Nominal panels were formed for consensus, systematic search of information, development of clinical questions, processing and grading of recommendations, internal validation by peers, and external validation of the final document. The quality criteria of the AGREE II instrument were followed.
Results: The various panels answered the 37 questions related to maternal and fetal care in SLE, RA, and APS, as well as to the use of antirheumatic drugs during pregnancy and lactation. The recommendations were discussed and integrated into a final manuscript. Finally, the corresponding algorithms were developed. We present the recommendations for pregnant women with SLE in this first part.
Conclusions: We believe that the Mexican clinical practice guidelines for the management of pregnancy in women with SLE integrate the best available evidence for the treatment and follow-up of patients with these conditions.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.reuma.2014.11.005 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
BIOCHEMICAL MARKERS OF MISCARRIAGE ASSOCIATED WITH THE INTRAPLACENTAL ACCUMULATION OF 137Cs.
Probl Radiac Med Radiobiol
December 2024
State Institution «Ukrainian Сenter of Maternity and Childhood of the National Аcademy of Мedical Sciences of Ukraine», 8 Platona Mayborody Str., Kyiv, 04050, Ukraine.
Unlabelled: The impact of the environment on human health in modern conditions cannot be underestimated. The study of thepathogenesis of disease is impossible without establishing the factors of destabilization of biological membranes.The article highlighted the problem of lipid peroxidation and antioxidant defense associated with the accumulationof radiocesium in the placenta.
View Article and Find Full Text PDFExcessive hypercholesterolaemia during pregnancy as a risk factor for endothelial dysfunction in pre-eclampsia.
J Physiol
December 2024
Department of Obstetrics & Gynecology, University of Alberta, Edmonton, AB, Canada.
Pregnancy induces significant changes in the maternal cardiovascular system, and insufficient vascular endothelial adaptations to pregnancy contribute to the development of pregnancy complications such as pre-eclampsia. Pre-eclampsia is not only a major cause of maternal morbidity and mortality, but also a significant risk factor for the development of later-life cardiovascular disease. However, the specific mechanisms underlying the pathophysiology of pre-eclampsia, as well as the mechanisms for an increased susceptibility to cardiovascular disease later in life, are not fully characterized.
View Article and Find Full Text PDFSafety of vaginal breech delivery following an unsuccessful external cephalic version: a comparative study.
Arch Gynecol Obstet
December 2024
Tel Aviv University School of Medicine, Tel Aviv, Israel.
Objective: To determine whether patients undergoing a trial of labor with a breech presentation following a failed attempt of external cephalic version (ECV) are at increased risk of adverse maternal and neonatal outcomes.
Methods: This retrospective cohort study was conducted at a single university-affiliated medical center. The study group comprised women with singleton pregnancies at term, categorized into three groups: those who underwent a failed external cephalic version (ECV) and subsequently attempted a trial of breech delivery (Breech-failed-ECV group), those who attempted an assisted vaginal breech delivery without a prior ECV attempt (Breech-no-ECV group), and those with vertex presentation following a successful ECV (Vertex-ECV).
Angiogenic Markers in Gestational Diabetes and their Association with Placental Dimensions.
Mol Cell Biochem
December 2024
Department of Mother and Child Health, Interactive Research School for Health Affairs (IRSHA), Bharati Vidyapeeth (Deemed to Be University), Pune-Satara Road, Pune, 411043, India.
GDM is an increasing global concern, with its etiology not fully understood, though altered placental function is likely to play a role. Placental angiogenesis, essential for sufficient blood flow and nutrient exchange between mother and fetus, may be affected by GDM. However, the role of angiogenic markers in GDM remains unclear.
View Article and Find Full Text PDFEthical issues in perinatal communication.
Eur J Pediatr
December 2024
Obstetrics and Obstetrical Pathology Unit, Department of Women's and Child Health and Public Health Sciences, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.
Unlabelled: Advancements in neonatal critical care continue, enhancing perinatal communication is essential to address the bioethical challenges faced. In perinatal care, various life-limiting or life-threatening conditions that address ethical issues can arise, both during the prenatal and postnatal phases. The diagnosis, prognosis, and potential treatment of these conditions significantly influence the lives of both the unborn child and the newborn, thereby directly impacting parental choices and experiences.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!