The total synthesis of (+)-crocacin D has been achieved in 15 steps (9 isolated intermediates) and 14% overall yield from commercially available starting materials and using (+)-crocacin C as a key intermediate. A number of simplified analogues and their biological activities are also reported.
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| http://dx.doi.org/10.1016/j.bmc.2015.01.008 | DOI Listing |
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