We describe five validation trials of new vacuum sealing technologies that change the approach to the preanalytic "front end" of specimen transport, handling, and processing and illustrate their adaptation and integration into existing Lean laboratory operations with reduction in formalin use and personnel exposure to this toxic and potentially carcinogenic fixative. These trials provide histologic assessment by numerous pathologists of tissues processed in this new paradigm and define the financial advantages of applying this technology to the postanalytic or "back end" process of tissue storage. We conclude that the TisssueSAFE and SealSAFE vacuum sealing systems are both promising technologies for preserving fresh human specimens that can promote a safer environment by markedly reducing formalin use in operating room theaters and can minimize formalin use by laboratories.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/978-3-319-13957-9_2 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Flexible disk ultramicroelectrode: Facile preparation and high-resolution scanning electrochemical microscopy imaging.
Anal Chim Acta
January 2025
State Key Laboratory of Electroanalytical Chemistry, Jilin Province Key Laboratory of Low Carbon Chemical Power, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130022, Jilin, China; School of Applied Chemistry and Engineering, University of Science and Technology of China, Hefei, 230026, Anhui, China. Electronic address:
Background: Scanning electrochemical microscopy (SECM) is a kind of scanning probe technology that enables the obtainment of surface morphology and electrochemical information by recording changes in Faraday current triggered by the movement of probe.
Results: In this work, flexible disk ultramicroelectrode (UME) with highly repeatable geometry are fabricated through a simple and universal strategy that involves vacuum pulling the glass capillaries inserted with platinum wire (gold wire, carbon fiber, etc.), followed by a rapidly heated sealing and polishing process.
Identification and treatment of -induced diabetic foot ulcer: a case report and microbiome analysis.
Front Med (Lausanne)
December 2024
Department of Clinical Laboratory, Sir Run Run Hospital, Nanjing Medical University, Nanjing, China.
Article Synopsis
- Diabetic foot ulcers (DFUs) can lead to severe complications like amputation if not treated promptly, often due to delays in care.
- A 56-year-old patient experienced a DFU linked to a bacterial infection from poultry exposure, requiring multiple debridement surgeries and targeted antibiotic treatment.
- Effective management of DFUs involves adjusting antibiotic therapies based on identified pathogens to reduce mortality and prevent irreversible amputations.
Peptidomic Analysis Reveals Temperature-Dependent Proteolysis in Rainbow Trout () Meat During Sous-Vide Cooking.
Proteomes
November 2024
Department of Aquatic Bioscience, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1, Yayoi, Bunkyo-ku, Tokyo 113-865, Japan.
Sous vide, a cooking method that involves vacuum-sealed fish at low temperatures, yields a uniquely tender, easily flaked texture. Previous research on sous-vide tenderization has focused on thermal protein denaturation. On the other hand, the contribution of proteases, activated at low temperatures in fish meat, has been suggested.
View Article and Find Full Text PDFPerioperative therapies and techniques to enhance penile dimensional and functional outcomes following inflatable penile prosthesis implantation: a contemporary 10-year systematic review.
Asian J Androl
December 2024
Department of Maternal Infant and Urologic Sciences, "Sapienza" University of Rome, Policlinico Umberto I Hospital, Rome 00161, Italy.
Implantation of inflatable penile prosthesis should be considered as a definitive treatment of erectile dysfunction. However, the sole procedure might not allow for optimal dimensional and functional outcomes. The aim of this study was to systematically review the literature and present the findings on the optimal choice of perioperative methods, surgical techniques, and pharmacotherapy to improve penile length, curvature, and erectile function.
View Article and Find Full Text PDFPaper-Based Device for Phenolic Content Determination in Tea Extracts.
Phytochem Anal
December 2024
Department of Chemistry, Colorado State University, Fort Collins, Colorado, USA.
Introduction: Phenolic compounds garner interest in developing medicines, nutraceuticals, and cosmeceuticals based on natural products. The quantity of phenolic compounds in a sample is commonly determined via spectrophotometry; however, this instrumented technique is relatively laborious and time consuming and requires a large amount of reagents.
Objective: This work aimed to develop a simple, point-of-need colorimetric sensor to rapidly determine total phenolic content (TPC) in tea extracts.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!