Facile synthesis of magnetic homochiral metal-organic frameworks for "enantioselective fishing".

Chem Commun (Camb)

Beijing National Laboratory for Molecular Sciences, Institute of Analytical Chemistry, College of Chemistry and Molecular Engineering, Peking University, Beijing, 100871, China.

Published: February 2015

Magnetic functionalized homochiral metal-organic frameworks (MOFs) were prepared and applied to efficient enantioselective fishing of chiral drug intermediates. Under optimized conditions, the enantiomeric excess (ee) value as high as 85.2% was achieved for methyl phenyl sulfoxide (MPS) within 3 min.

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Source
http://dx.doi.org/10.1039/c4cc09988eDOI Listing

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