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A perspective on the use of patient-reported experience and patient-reported outcome measures in ambulatory healthcare.
Expert Rev Pharmacoecon Outcomes Res
January 2025
RAND Corporation, Santa Monica, CA, USA.
Introduction: Patient-reported experience measures (PREMs) are patient reports about their healthcare, whereas patient-reported outcome measures (PROMs) are reports about their functioning and well-being regarding physical, mental, and social health. We provide a perspective on using PREMs and PROMs in ambulatory healthcare.
Areas Covered: We conducted a narrative review of the literature about using PREMs and PROMs in research and clinical practice, identified challenges and possibilities for addressing them, and provided suggestions for future research and clinical practice.
Psychosocial impact associated with a multicancer early detection test (PATHFINDER): a prospective, multicentre, cohort study.
Lancet Oncol
January 2025
Health Systems and Population Health, University of Washington, Seattle, WA, USA. Electronic address:
Background: PATHFINDER was a prospective cohort study of multicancer early detection (MCED) testing in an outpatient ambulatory population. The aim of this study is to report the patient-reported outcomes (PROs) collected as secondary and exploratory measures in the PATHFINDER study.
Methods: PATHFINDER is a prospective, multicentre, cohort study that enrolled existing healthy ambulatory outpatients at seven health networks in the USA, including hospitals, academic medical centres, and integrated health systems.
The determination of biochemical parameters plays an important role in the veterinary care of alpacas, as it can provide an overview of the integrity and function of various organs and metabolic states. Various reference intervals are available for interpreting biochemical results in alpacas, but physiological variations due to age, sex or season should also be considered. Particularly, information on the influence of age is scarce.
View Article and Find Full Text PDFDisparate Use of Diagnostic Modalities for Patients With Limited English Proficiency and Neurologic Disorders.
Neurol Clin Pract
April 2025
Department of Neurology (AS), Massachusetts General Hospital, Harvard Medical School, Boston; Department of Public Health Sciences (RBAB), University of North Carolina at Charlotte; Disparities Research Unit, Department of Medicine, Massachusetts General Hospital; Department of Psychiatry, Harvard Medical School; Harvard Medical School (DH, SW), Boston; and City University of New York at Hunter College (DH, SW).
Background And Objectives: Limited English proficiency (LEP) impairs health access-including outpatient specialty care-and quality care, i.e., inappropriate use of diagnostic tests.
View Article and Find Full Text PDFAwakening not associated with an increased rate of cortisol secretion.
Proc Biol Sci
January 2025
Laboratory for Integrative Neuroscience and Endocrinology, University of Bristol, Bristol BS1 3NY, UK.
Cortisol is released upon activation of the hypothalamic-pituitary-adrenal axis, varies across the day, possesses an underlying diurnal rhythm and is responsive to stressors. The endogenous circadian peak of cortisol occurs in the morning, and increases in cortisol observed post-awakening have been named the cortisol awakening response (CAR) based on the belief that the act of waking up stimulates cortisol secretion. However, objective evidence that awakening induces cortisol secretion is limited.
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