Objective: This study compared the marginal adaptation of mineral trioxide aggregate (MTA) and MTA-like materials as root-end fillings after incubation in phosphate buffer saline (PBS), a synthetic tissue fluid, for either 1 week or 2 months.
Materials And Methods: In this experimental study, seventy-two extracted human single-rooted teeth were prepared and obturated with gutta-percha and AH26 sealer. The apical 3 mm of the roots were resected. Root-end cavities were prepared with an ultrasonic retrotip. The specimens were randomly divided into three groups (n=24) and filled with either ProRoot MTA, OrthoMTA, or RetroMTA. Half of the specimens in each group were stored in PBS for 1 week the other half for 2 months. Epoxy resin replicas from the resected root-end surfaces and longitudinally sectioned roots were fabricated. The gaps at the material/dentin interface were measured using a scanning electron microscope (SEM). Transversal, longitudinal, and overall gap sizes were measured. The data were analyzed using Kruskal-Wallis and Mann-Whitney tests. The significance level was set at p < 0.05.
Results: There were no significant differences between the marginal adaptation of ProRoot MTA, RetroMTA, and OrthoMTA in both transverse and longitudinal sections after incubation for either 1 week or 2 months (p > 0.05). In addition, the test groups were not significantly different regarding the overall mean gap values (p > 0.05).
Conclusion: Under the conditions of this study, there was no difference between the marginal adaptation of ProRoot MTA, OrthoMTA, and RetroMTA as root-end filling materials after exposure to PBS for either 1 week or 2 months.
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Background: In proton radiotherapy, the steep dose deposition profile near the end of the proton's track, the Bragg peak, ensures a more conformed deposition of dose to the tumor region when compared with conventional radiotherapy while reducing the probability of normal tissue complications. However, uncertainties, as in the proton range, patient geometry, and positioning pose challenges to the precise and secure delivery of the treatment plan (TP). In vivo range determination and dose distribution are pivotal for mitigation of uncertainties, opening the possibility to reduce uncertainty margins and for adaptation of the TP.
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January 2025
Conservative Dentistry Department, Faculty of Dentistry, Mansoura University, Mansoura, Postal Code, 35516, Egypt.
Background: Hydrophilic monomer 2-hydroxyethyl methacrylate (HEMA)-free adhesive systems are gaining increasing popularity nowadays. Although the addition of HEMA to dental adhesives improves dentin wettability and resin diffusion into demineralized collagen fibrils, HEMA's high hydrophilicity can lead to hydrolytic degradation of the adhesive interface. Thus, HEMA-free adhesive systems have been developed.
View Article and Find Full Text PDFBackground/objectives: Adaptive optics ophthalmoscopy (AOO) has the potential to provide insights into AMD pathology and to assess the risk of progression. We aim to utilise AOO to describe detailed features of intermediate AMD and to characterise microscopic changes during atrophy development.
Subjects/methods: Patients with intermediate AMD were recruited into PINNACLE, a prospective observational cohort study.
J Coll Physicians Surg Pak
January 2025
Department of Stomatology, The Second People's Hospital of Hefei and Hefei Hospital Affiliated to Anhui Medical University, Hefei, Anhui, China.
Objective: To investigate the effects of bulk-fill, resin-based composite types (high or low viscosity) on the internal adaptation of Class V restorations.
Study Design: Experimental study. Place and Duration of the Study: Hefei Stomatological Hospital, Hefei, China, from October 2022 to December 2023.
Sci Total Environ
January 2025
Department of Microbiology, Pondicherry University, Kalapet, Puducherry 605014, India. Electronic address:
Climate change-induced rise in sea surface temperatures has led to an increase in the frequency and severity of coral bleaching events, ultimately leading to the deterioration of coral reefs, globally. However, the reef-building corals have an inherent capacity to acclimatize to thermal stress on pre-exposure to high temperatures by altering their endosymbiotic Symbiodiniaceae community composition towards a thermal tolerant composition. This reorganisation may become an important tool in coral's resilience to rapid environmental change.
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