Introduction: In Brazil, visceral leishmaniasis (VL) has spread to various regions. This study reports canine cases of VL in Barra Mansa, where human VL cases were recently reported.
Methods: Using the human index case, a canine survey was performed by dual-path platform immunochromatography and enzyme-linked immunosorbent assay. Seropositive animals were euthanized. Cultures were collected to detect Leishmania parasites.
Results: Serological tests detected 141 canine VL cases, and Leishmania chagasi were isolated from 82.2% animals.
Conclusions: Leishmania chagasi is in circulation in Barra Mansa. This study broadens information on the parasite's distribution in the State of Rio de Janeiro.
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http://dx.doi.org/10.1590/0037-8682-0042-2014 | DOI Listing |
Rev Bras Parasitol Vet
October 2024
Departamento de Biologia Animal, Instituto de Ciências Biológicas e da Saúde, Universidade Federal Rural do Rio de Janeiro - UFRRJ, Seropédica, RJ, Brasil.
Prim Care Companion CNS Disord
March 2024
Universidade Federal do Rio de Janeiro, Instituto de Psiquiatria, Depression Resistant Ambulatory, Rio de Janeiro RJ, Brazil.
To evaluate traditional versus guided cognitive-behavioral therapy (CBT) with the use of applications and technological innovations. A systematic search was conducted in the MEDLINE/PubMed, SciELO, and Cochrane Library databases and included randomized controlled trials (RCTs) from inception to March 30, 2023, with no language restrictions. Only RCTs with available text were included, which is valid from the app versus traditional CBT comparison perspective.
View Article and Find Full Text PDFJ Bras Pneumol
March 2024
. Faculdade de Medicina, Universidade Federal de Goiás, Goiânia (GO) Brasil.
Objective: To assess prescription patterns for short-acting b2 agonists (SABAs) and other asthma medications in asthma patients treated by specialists and participating in the SABA use IN Asthma (SABINA) study in Brazil.
Methods: This was an observational, cross-sectional study conducted at five sites in different regions of Brazil. The primary endpoints were to record SABA prescriptions and obtain data on over-the-counter (OTC) SABA purchases at the pharmacy.
Antiinflamm Antiallergy Agents Med Chem
August 2024
Laboratório de Farmacologia da Inflamação e Nocicepção, Programa de Pós-Graduação em Medicina Veterinária, Instituto de Veterinária, Universidade Federal Rural do Rio de Janeiro, Seropédica, RJ, Brasil.
Background: The development of analgesic and anti-inflammatory drugs plays a crucial role in modern medicine, aiming to alleviate pain and reduce inflammation in patients. Opioids and nonsteroidal anti-inflammatory drugs are groups of drugs conventionally used to treat pain and inflammation, but a wide range of adverse effects and ineffectiveness in some pathological conditions leads us to search for new drugs with analgesic and anti-inflammatory properties.
Objectives: In this regard, the authors intend to investigate the ((2s,6s)-6-ethyl-tetrahydro-2h-pyran- 2-yl) methanol compound (LS20) on pain and acute inflammation.
Einstein (Sao Paulo)
December 2023
Laboratory of Endocrinology and Translational Medicine, Universidade Federal de São Paulo, São Paulo, SP, Brazil.
Objective: We hypothesized that perinatal manipulations of the nitrergic system would affect adult animal behaviors.
Methods: We tested this hypothesis by perinatally administering N(G)-Nitro-L-arginine methyl ester (L-NAME), a non-specific antagonist of nitric oxide synthase for 15 days and assessed anxiety- and depression-like behaviors in adult mice. At 70 days of age, the mice were subjected to a battery of tests consisting of the open-field, light/dark box, forced swim, and tail-flick tests.
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