AI Article Synopsis
- Plant cell, tissue, and organ cultures (PCTOC) are increasingly used to produce high molecular weight molecules for flavors, fragrances, and food additives.
- These products, while cultivated in a contamination-free environment, may contain unwanted components and potential toxins from the culture process.
- Safety assessment of PCTOC products is crucial and involves evaluating starting materials, production methods, and the final product for chemical, biological properties, and toxicity before commercialization.
Article Abstract
Plant cell, tissue and organ cultures (PCTOC) have become an increasingly attractive alternative for the production of various high molecular weight molecules which are used as flavourings, fragrances, colouring agents and food additives. Although PCTOC products are cultivated in vitro in a contamination free environment, the raw material produced from PCTOC may contain many components apart from the target compound. In some cases, PCTOC raw materials may also carry toxins, which may be naturally occurring or accumulated during the culture process. Assessment of the safety of PCTOC products is, therefore, a priority of the biotech industries involved in their production. The safety assessment involves the evaluation of starting material, production process and the end product. Before commercialisation, PCTOC products should be evaluated for their chemical and biological properties, as well as for their toxicity. In this review, measures and general criteria for biosafety evaluation of PCTOC products are addressed and thoroughly discussed.
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| http://dx.doi.org/10.1016/j.foodchem.2014.12.075 | DOI Listing |
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