Oral ulcers are common and can have many causes, making diagnosis challenging. This article provides an overview of common oral ulcers and an algorithmic approach to establishing the correct diagnosis. Factors such as duration, pattern of recurrence, clinical appearance, mucosal location, and presence or absence of systemic symptoms are useful clues to determining an ulcer's cause.
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| http://dx.doi.org/10.1097/01.JAA.0000459826.63026.67 | DOI Listing |
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Effectiveness of oral platelet lysate gel to treat oral mucosal manifestations associated with chronic graft versus host disease.
Blood Transfus
January 2025
Apheresis and Cellular Therapy Unit, Hemotherapy and Hemostasis Department, Institute of Cancer and Hematological Diseases, Hospital Clínic Universitari de Barcelona, Barcelona, Spain.
Background: Chronic graft-vs-host disease (cGvHD) is a severe immune-mediated complication that affects patients following allogeneic hematopoietic stem cell transplantation (allo-HSCT). Oral manifestations of cGvHD, such as ulcers and mucosal inflammation, significantly impair quality of life and often require long-term treatment. Existing therapies provide limited relief, prompting the exploration of new approaches, including the use of autologous platelet lysate (PL) gel for its regenerative properties.
View Article and Find Full Text PDFMenrath ulcers in cats: four cases (2014-2023).
J Small Anim Pract
January 2025
Langford Veterinary Services, Langford, UK.
Objectives: To report the clinical presentation, treatment and outcomes of four cats diagnosed with Menrath ulcers causing significant oral haemorrhage.
Materials And Methods: For all cats, data on signalment, history, physical examination, treatment and outcomes were collected by reviewing medical records. Information regarding outcomes was collected from communication logs between primary care veterinarians and owners, and the original case clinicians after discharge of the patient from the hospital.
Synergistic Effects of NO/HS Gases on Antibacterial, Anti-inflammatory, and Analgesic Properties in Oral Ulcers Using a Gas-Releasing Nanoplatform.
Acta Biomater
January 2025
School and Hospital of Stomatology, Wenzhou Medical University, Wenzhou, 325027, P. R. China. Electronic address:
Article Synopsis
- Oral mucosal wounds are susceptible to inflammation and complications due to exposure to microorganisms, which can hinder daily activities and diminish quality of life.
- A novel therapeutic nanoplatform, DATS@Arg-EA-SA, has been developed to target these wounds by combining guanidinated dendritic peptides with diallyl trisulfide (DATS), providing both antimicrobial and anti-inflammatory effects.
- This nanoplatform effectively eliminates various bacteria, including drug-resistant strains like MRSA, and enhances healing by promoting the transition of inflammatory cells and alleviating pain, making it a promising solution for oral wound treatment.
The Dermatologic Oral Examination: Navigating the Oral Dermatoses Map.
J Am Acad Dermatol
January 2025
Mayo Clinic Arizona, Department of Dermatology, Scottsdale, AZ, USA.
Traditionally, dermatological education emphasizes hair, skin and nails in its curriculum. There is a practice gap with regard to knowledge of normal oral mucosa variants, performance of the oral examination, and competence in diagnosing and treating oral mucosal disorders. The oral mucosa falls within the purview of dermatology.
View Article and Find Full Text PDFThe provision of wound care and management in a community healthcare setting: an exploratory study.
J Wound Care
January 2025
Nursing and Health Care, School of Health Sciences, South East Technological University, Waterford City, Ireland.
Objective: Wound management can be costly and challenging to the health services' scarce resources. Information regarding the number of wounds in a community care setting and their associated aetiology will provide nurses and nurse managers with an insight into the specific needs of these clients with wounds and highlight areas where care or services can be improved or further developed. This research aimed to establish the prevalence and aetiology of wounds, the current delivery of wound care, wound documentation and referral pathways in an Irish community care setting.
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