Visual statistical learning (VSL) is the ability to extract the joint and conditional probabilities of shapes co-occurring during passive viewing of complex visual configurations. Evidence indicates that even infants are sensitive to these regularities (e.g., Kirkham et al., 2002). However, there is continuing debate as to whether VSL is accompanied by conscious awareness of the statistical regularities between sequence elements. Bertels et al. (2012) addressed this question in young adults. Here, we adapted their paradigm to investigate VSL and conscious awareness in children. Using the same version of the paradigm, we also tested young adults so as to directly compare results from both age groups. Fifth graders and undergraduates were exposed to a stream of visual shapes arranged in triplets. Learning of these sequences was then assessed using both direct and indirect measures. In order to assess the extent to which learning occurred explicitly, we also measured confidence through subjective measures in the direct task (i.e., binary confidence judgments). Results revealed that both children and young adults learned the statistical regularities between shapes. In both age groups, participants who performed above chance in the completion task had conscious access to their knowledge. Nevertheless, although adults performed above chance even when they claimed to guess, there was no evidence of implicit knowledge in children. These results suggest that the role of implicit and explicit influences in VSL may follow a developmental trajectory.
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http://dx.doi.org/10.3389/fpsyg.2014.01541 | DOI Listing |
Drug Des Devel Ther
January 2025
School of Medicine, Kyungpook National University and Department of Clinical Pharmacology and Therapeutics, Kyungpook National University Hospital, Daegu, 41944, Republic of Korea.
Background: YYD601 is a new dual delayed-release formulation of esomeprazole, developed to enhance plasma exposure and prolong the duration of acid suppression.
Purpose: This study aimed to evaluate the safety, pharmacokinetic (PK), and pharmacodynamic (PD) profiles of YYD601 20 mg following single and multiple oral administrations in healthy, fasting adult Koreans, and to compare these outcomes to those of the conventional esomeprazole 20 mg capsule.
Methods: A randomized, open-label, two-period crossover study was conducted in 28 participants, who were divided into two treatment groups: one group received YYD601 20 mg, and the other received conventional esomeprazole 20 mg, once daily for five consecutive days.
Unlabelled: It is currently estimated that every 15 minutes an infant is born with opioid use disorder and undergoes intense early life trauma due to opioid withdrawal. Clinical research on the long-term consequences of gestational opioid exposure reports increased rates of social, conduct, and emotional disorders in these children. Here, we investigate the impact of perinatal opioid exposure (POE) on behaviors associated with anhedonia and stress in male and female Sprague Dawley rats.
View Article and Find Full Text PDFOccup Ther Int
January 2025
Occupational Therapy Department, University of the Western Cape, Cape Town, South Africa.
Individuals diagnosed with tuberculosis (TB) and multidrug-resistant (MDR) TB may struggle to return to work after they have completed a rehabilitation program. Multidrug-resistant tuberculosis (MDRTB) has been seen as a condition that is resistant to treatment, hence causing individuals to be economically in-active for considerable periods of time. The aim of the current study was to explore the views of individuals living with MDRTB, individuals with TB, and health professionals treating individuals with TB and MDRTB about the development of a vocational rehabilitation program.
View Article and Find Full Text PDFBio Protoc
January 2025
Department of Structural and Cellular Biology, Tulane University, New Orleans, LA, USA.
The initiation and progression of prostate cancer (PCa) are associated with aging. In the history of age-related PCa research, mice have become a more popular animal model option than any other species due to their short lifespan and rapid reproduction. However, PCa in mice is usually induced at a relatively young age, while it spontaneously develops in humans at an older age.
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