It has been shown that it is possible to predict the CD 34+ hematopoietic progenitor cell dose from collection procedures on TerumoBCT COBE Spectra® cell separator platform using simple variables available at the start of the procedure. In this article, we demonstrate that this can be done simply and reliably using TerumoBCT Spectra Optia® ("Optia") cell separator platform with a very close correlation between predicted and actual results (correlation coefficient 0.956). This knowledge can be used to optimize apheresis sessions and to minimize harmful effects and costs. In addition, we have shown differences in collection efficiency between healthy donors and cancer patients undergoing autologous donation. Finally, we have shown a small but significant improvement in collection efficiency for the Optia platform compared with the COBE Spectra platform.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1002/jca.21380 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Preparation and stability of chebulagic acid and chebulinic acid from Terminalia chebula and their biological activity.
Pak J Pharm Sci
January 2025
College of Pharmacy, Liaoning University of Traditional Chinese Medicine, Dalian, China/Province Multi-Component Chinese Medicine Engineering Technology Research Center of Liaoning, Dalian, China/Modern Traditional Chinese Medicine Research and Engineering Laboratory of Liaoning, Dalian, China.
Chebulagic acid and chebulinic acid are the two tannin compounds with the highest content in Terminalia chebula, they were separated by ODS column eluted with 20% methanol and 35% methanol, respectively. The compounds were identified by comparing the data of H NMR and C NMR with the literature; HPLC method was used to investigate the stable storage conditions of chebulagic acid and chebulinic acid; lipopolysaccharide (LPS) induced in vivo inflammation model and RAW264.7 macrophage in vitro inflammatory model to evaluate the anti-inflammatory activities of chebulagic acid and chebulinic acid.
View Article and Find Full Text PDFExploring the antioxidant, anticancer properties and phenolic composition of Anchusa strigosa.
Pak J Pharm Sci
January 2025
Department of Anatomy, College of Veterinary Medicine, University of Mosul, Mosul, Iraq.
This study utilised A. strigose, a herbaceous plant widely used in folk medicine and commonly distributed in the Middle East. The antioxidant activity in the extracts of this plant has been underscored.
View Article and Find Full Text PDFA Native LH1-RC-HiPIP Supercomplex from an Extremophilic Phototroph.
Commun Biol
January 2025
Faculty of Science, Ibaraki University, Mito, Japan.
Halorhodospira (Hlr.) halophila strain BN9622 is an extremely halophilic and alkaliphilic purple phototrophic bacterium and has been widely used as a model for exploring the osmoadaptive and photosynthetic strategies employed by phototrophic extreme halophiles that enable them to thrive in hypersaline environments. Here we present the cryo-EM structures of (1) a unique native Hlr.
View Article and Find Full Text PDFChromosome-level genome assembly, annotation, and population genomic resource of argali (Ovis ammon).
Sci Data
January 2025
Key Laboratory of Ecological Safety and Sustainable Development in Arid Lands, Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences, Urumqi, 830011, China.
Argali stands as the largest species among wild sheep in Central and East Asia, with a concerning rate of decline estimated at 30%. The intraspecific taxonomy of argali remains contentious due to limited genomic data and unclear geographic separation. In this study, we constructed a chromosome-level genome assembly and annotation for the Tibetan argali (O.
View Article and Find Full Text PDFProteome changes during the germination and early seedling development of carnauba palm (Copernicia prunifera) under skotomorphogenic conditions.
J Proteomics
January 2025
Departamento de Bioquímica e Biologia Molecular, Programa de Pós-Graduação em Bioquímica, Universidade Federal do Ceará, Fortaleza, Brazil. Electronic address:
We analyze the proteome changes during the development of the carnauba palm (Copernicia prunifera) seedlings under skotomorphogenic conditions, by separating the embryo into its two components: haustorium (HA) and cotyledonary petiole (CP) and established the descriptive and quantitative proteomes of these tissues across four developmental stages. 5205 proteins were identified in HA and 6028 in CP. These proteomes are rich in proteins known to maintain the skotomorphogenic state, and in a complete set of proteins involved in cellular respiration and biosynthesis of secondary metabolites.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!