Because of their high prevalence and constant increase, and their impact in terms of human and financial costs, non-communicable diseases (NCD) represent an important public health issue. Recognizing this alarming situation, the international Community took decisive commitments to reduce the spread of this epidemic of the 21st century. These commitments have been translated in the national prevention and care policies. In the Wallonie-Brussels Federation (WBF), a set of health policies to prevent non communicable diseases was initiated. The objectives of the study were to describe, explore promotion and primary and secondary prevention against NCDs policies in WBF, to highlight the main challenges and issues, and to provide some recommendations to concerned actors. To achieve the objectives of this study, a literature review and a qualitative approach were used. Semi-structured interviews of key stakeholders were conducted in WBF. It involved 14 actors selected for their involvement in the formulation and implementation of these policies. It appears that the Belgian institutional complexity, the lack of willingness of policymakers in prevention and health promotion, the lack of a comprehensive structured policy of prevention and health promotion and an absence of any coordination structure are the main obstacles facing the formulation and implementation of these policies.

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