Introduction: The report issued by the European Food Safety Agency (EFSA) in 2010 on nutrition and health claims, shows that there is no scientific evidence to support supplementation with branched chain amino acids (BCAAs). The aim of this study is to analyze the effects of consumption of BCAAs in endurance sports.
Methods: A literature review on the current state of the effect of consumption of dietary supplements of BCAAs. We conducted a search in the PubMed database and snowball strategy.
Inclusion Criteria: Spanish / English randomized clinical trial related to the consumption of BCAAs, leucine, valine and isoleucine in endurance sports and its effects on muscle damage, athletic performance, central fatigue, anabolic signals during recovery and immune system response published in any country until May 2014.
Results: Out of 330 studies identified, 14 met the inclusion criteria. The mean of subjects participating in the study was (11.36±7.43). Only two studies included a group of women. The sports that we found in the studies were: run, cycling, combining cycling and running, Olympic distance triathlon and one study included 2 groups of athletes (Olympic distance triathletes and runners). The effects of BCAAs and muscle damage, athletic performance, central fatigue, anabolic signals during recovery period and immune response were studied at different times: before, during and after training or a combination of these.
Discussion: It is observed that there is a lesser degree of pain and muscle damage, less perceived exertion and mental fatigue, greater anabolic response in recovery period and improved immune response when supplemented with BCAAs, notwithstanding its decision before or during physical activity does not improve athletic performance. No consensus was found in the dose and timing of the most effective decision, although it is more effective if there is 2-3/1/1g relationship between leucine / isoleucine and valine amino acids.
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http://dx.doi.org/10.3305/nh.2015.31.2.7852 | DOI Listing |
Front Plant Sci
January 2025
Plant Biochemistry and Physiology, Bielefeld University, Bielefeld, Germany.
The network of antagonistic, neutral, and synergistic interactions between (micro)organisms has moved into the focus of current research, since in agriculture, this knowledge can help to develop efficient biocontrol strategies. Applying the nematophagous fungus as biocontrol agent to manage the root-knot nematode is a highly promising strategy. To gain new insight into the systemic response of plants to a plant-parasitic nematode and a nematophagous fungus, was inoculated with and/or and subjected to transcriptome and metabolome analysis of leaves.
View Article and Find Full Text PDFChem Sci
January 2025
School of Chemistry, University of Glasgow Joseph Black Building, University Avenue Glasgow G12 8QQ UK
To overcome the limitations of using large extrinsic chromophores for biological imaging, fluorescent unnatural α-amino acids have been widely adopted as intrinsic peptidic probes. Although various classes have been successfully utilised for imaging applications, novel amino acid probes readily prepared through operationally simple synthetic methodology are still required. Here, we report a new approach for the synthesis of unnatural α-amino acids a one-pot process involving activation and palladium-catalysed arylation of tyrosine.
View Article and Find Full Text PDFCurr Dev Nutr
October 2024
Clinical Nutrition Research Centre (CNRC), Singapore Institute of Food and Biotechnology Innovation (SIFBI), Agency for Science, Technology and Research (A∗STAR), Singapore, Singapore.
Complementing discourse following a February 2023 event on dietary protein needs in Southeast Asia (SEA), this symposium report summarizes the region's protein intake, while simultaneously examining the impact of dietary shift toward complementary and alternative proteins and their health implications. It highlights the importance of protein quality in dietary evaluations, optimal intake, and sustainability, advocating for environmentally conscious protein production and innovation in future foods. Discussion points, expert opinions, national nutrition data, and relevant literature, addressing protein intake and quality, their impact on human health, and various technologies for future foods production, have been included.
View Article and Find Full Text PDFBioinform Biol Insights
January 2025
Department of Microbiology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Aims: Antibiotic resistance is currently a major challenge to scientists. Thus, attempts have been made to develop new compounds with antimicrobial activity. In this research, a new antimicrobial peptide with antibacterial activity was isolated from the plant .
View Article and Find Full Text PDFBiochem Biophys Rep
March 2025
Faculty of Pharmacy, Yasuda Women's University, 6-13-1 Yasuhigashi, Asaminami Ward, Hiroshima City, Hiroshima, 731-0153, Japan.
Methylmalonic acid (MMA) is a small molecule produced during the metabolism of propionate and branched-chain amino acids. Recently, it has been reported that the blood concentration of MMA increases with age and promotes lung cancer metastasis. However, little is known regarding its effects on cancers other than lung cancer.
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