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Effects of Mediterranean diet supplemented with silybin-vitamin E-phospholipid complex in overweight patients with non-alcoholic fatty liver disease. | LitMetric

AI Article Synopsis

  • Non-alcoholic fatty liver disease (NAFLD) is the most prevalent liver disease globally, prompting research into dietary interventions.
  • The study compares the effects of the Mediterranean diet versus a diet supplemented with silybin, phosphatidylcholine, and vitamin E in overweight individuals with NAFLD.
  • Results indicate that both the Mediterranean diet alone and in combination with the supplement led to significant improvements in BMI, waist circumference, cholesterol levels, and triglycerides, especially highlighting notable changes in the group that received the supplement.

Article Abstract

Background: Non-alcoholic fatty liver disease is the most common liver disease worldwide.

Aim: The aim of this study is to compare the metabolic effects of the Mediterranean diet versus the diet associated with silybin, phosphatidylcholine and vitamin E complex in overweight patients with non-alcoholic fatty liver disease.

Methods: Thirty Caucasian overweight patients were randomized into three groups of 10 (Groups A, B and C). A personalized Mediterranean diet was started in Group A and B patients. In association with the diet, Group B patients were given Realsil complex, daily, for 6 months. Group C patients refused any treatment.

Results: We showed that the Mediterranean diet alone, or in association with the Realsil complex, led to the significant variation in BMI, waist circumference, total cholesterol and triglycerides. We also observed a statistically significant decrease in homeostasis model assessment technique in Group B patients.

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Source
http://dx.doi.org/10.1586/17474124.2015.1004312DOI Listing

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