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Composite cardiovascular risk scores and neuropsychological functioning: a meta-analytic review. | LitMetric

AI Article Synopsis

Article Abstract

Background: The ability for patients to understand their risk for disease is important to early intervention and effective treatment. The link between individual cardiovascular risk factors and cognition has been well-established.

Purpose: This study investigated the relationship between cognition and a combination of these factors through a single composite risk score.

Methods: This study quantitatively summarized the strength of the association between composite cardiovascular risk scores and cognitive test performance using meta-analytic methods.

Results: One hundred and nine effect sizes were obtained from 19 studies employing 54,564 participants. Composite risk scores showed a significant association (r=-0.16) with cognitive test performance. Cognitive domain and age did not significantly modify this relationship.

Conclusions: Composite cardiovascular risk scores can be useful indicators of future cognition. The development of a dementia risk score using similar risk factors could aid in the assessment and lifestyle interventions of persons at risk for dementia.

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Source
http://dx.doi.org/10.1007/s12160-014-9681-0DOI Listing

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