Actualized by the ongoing discussion of whether childhood disintegrative disorder is a diagnostic entity, we describe a case which in every aspect fulfils the ICD-10 criteria. A girl with a previous normal development who, from the age of 60 months, experienced a regression during 2-3 months with significant co-morbid psychiatric symptoms, leaving her in a state of mental retardation and autism. A thorough somatic assessment was normal. The importance of recognition of the condition and an integrated child psychiatric and paediatric assessment is emphasized.
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