AI Article Synopsis
- This meta-analysis explored the placebo effect on itch, a symptom often overlooked in treatment studies.
- It analyzed data from 34 clinical trials involving patients with chronic itch from conditions like atopic dermatitis and psoriasis.
- Results showed that placebo treatment significantly reduced itch levels, indicating a notable role of placebo in managing these symptoms.
Article Abstract
Although placebo contributes to the effects of treatment for various symptoms and conditions, its effect on itch has rarely been investigated. In this meta-analysis, the magnitude of the placebo effect on itch was systematically investigated in clinical trials including patients with chronic itch due to atopic dermatitis, psoriasis, or chronic idiopathic urticaria. From searches in four databases, 34 articles were included in the quantitative analyses. Placebo treatment significantly decreased itch (1.3 out of 10, 95% confidence interval 1.02-1.61) compared with baseline itch (effect size 0.55), indicating that placebo effects have a considerable role in these patients' treatment.
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| http://dx.doi.org/10.1038/jid.2014.522 | DOI Listing |
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