Metastatic involvement of the heart is a rare occurrence and remains undiagnosed until autopsy. In some instances, patients may have cardiac symptoms, leading to ante-mortem diagnosis. Although most primary cancers have been documented to metastasize to heart, the existing literature on cancers of upper aero-digestive tract is an exception, with only a few reports. We report four cases of upper aero-digestive tract cancers, three of which arise from oral cavity, one from lower esophagus, metastasising to the myocardium, detected on 18 F - Fluoro-deoxy-glucose Positron Emission Tomography/Computed Tomography (FDG PET/CT) study , in the absence of related symptoms.
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http://dx.doi.org/10.1186/1470-7330-14-16 | DOI Listing |
Nutr Res Rev
November 2024
Department of Prosthodontics, Dental School, National and Kapodistrian University of Athens, Athens, Greece.
As the Mediterranean diet (MDi) has demonstrated a powerful preventative effect on various medical conditions, a positive effect on oral health may also be speculated. Tooth loss, pain or tooth mobility may discourage the consumption of specific food types, affecting MDi adherence. The aim of this study was to investigate the association between adherence to MDi and oral health in adult populations.
View Article and Find Full Text PDFNicotine Tob Res
November 2024
School of Health Sciences, University of East Anglia, UK.
Introduction: An estimated 78% of the total deaths attributable to smoking tobacco use occurred in low- and middle-income countries (LMICs) in 2019. In addition, smokeless tobacco increases the risk of all-cause mortality, all cancers including upper aero-digestive tract cancer, stomach cancer, ischaemic heart disease (IHD) and stroke; with 88% of the mortality burden being borne by the South-East Asian region. Evidence-based interventions from high income countries (HICs) are not easily transferable to LMICs, as patterns of tobacco use, health beliefs associated with tobacco use, and awareness of specific health risks vary substantially.
View Article and Find Full Text PDFCureus
June 2024
Otorhinolaryngology - Head and Neck Surgery, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth, Pune, IND.
Introduction Adenoid tissue is part of the first line of immunity of the upper aero-digestive tract. It is located in the postero-superior wall of the nasopharynx behind the choana. Adenoid hypertrophy, a common childhood disorder, significantly contributes to the pathogenesis of otitis media with effusion (OME), which is the leading cause of hearing impairment in young children.
View Article and Find Full Text PDFFront Public Health
May 2024
Department Prevention Cancer Environment, Centre Léon Bérard, U1296 INSERM Radiation, Defense, Health and Environment, Lyon, France.
Background: While overall head and neck cancer incidence decreases due to reduced tobacco and alcohol consumption, the incidence of HPV negative oral cavity squamous cell carcinoma (SCC) is raising in several industrialized countries, especially in non-smoking and non-drinking patients.
Case Presentation: We document a case of gingiva SCC in a 56 years old never-smoker patient reporting low alcohol consumption and unusual occupational solvent exposure. The HPV-negative lesion was surgically removed in 2018, and the patient remains in complete remission 4 years after recurrent surgery in 2019.
Immun Ageing
April 2024
Institute of Immunology, Genetics and Metabolism (INIGEM), Clinical Hospital 'José de San Martín', University of Buenos Aires (UBA), National Council for Scientific and Technological Research (CONICET), Av Córdoba 2351, C1120AAF, Buenos Aires, CABA, Argentina.
Background: The tonsils operate as a protection ring of mucosa at the gates of the upper aero-digestive tract. They show similarities with lymph nodes and participate as inductive organs of systemic and mucosal immunity. Based on the reduction of their size since puberty, they are thought to experience involution in adulthood.
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